1ocs
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1ocs.png|left|200px]] | ||
| - | + | ==Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.== | |
| - | + | <StructureSection load='1ocs' size='340' side='right'caption='[[1ocs]], [[Resolution|resolution]] 2.03Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ocs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocs OCA], [https://pdbe.org/1ocs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocs RCSB], [https://www.ebi.ac.uk/pdbsum/1ocs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocs ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SNX3_YEAST SNX3_YEAST] Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).<ref>PMID:9456318</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocs_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ocs ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | === | + | ==See Also== |
| - | + | *[[Sorting nexin 3D structures|Sorting nexin 3D structures]] | |
| - | + | == References == | |
| - | < | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
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[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | + | [[Category: Aufrere R]] | |
| - | [[Category: Aufrere | + | [[Category: Blondeau K]] |
| - | [[Category: Blondeau | + | [[Category: Cheruel S]] |
| - | [[Category: Cheruel | + | [[Category: Collinet B]] |
| - | [[Category: Collinet | + | [[Category: De La Torre F]] |
| - | [[Category: Graille | + | [[Category: Graille M]] |
| - | [[Category: Henkes | + | [[Category: Henkes G]] |
| - | [[Category: Janin | + | [[Category: Janin J]] |
| - | [[Category: Leulliot | + | [[Category: Leulliot N]] |
| - | [[Category: | + | [[Category: Li De La Sierra-Gallay I]] |
| - | [[Category: | + | [[Category: Minard P]] |
| - | [[Category: | + | [[Category: Poupon A]] |
| - | [[Category: | + | [[Category: Savarin P]] |
| - | [[Category: Sorel | + | [[Category: Sorel I]] |
| - | [[Category: Tilbeurgh | + | [[Category: Van Tilbeurgh H]] |
| - | + | [[Category: Zhou CZ]] | |
| - | [[Category: Zhou | + | |
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Current revision
Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.
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