1ocs

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{{Seed}}
 
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[[Image:1ocs.png|left|200px]]
 
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==Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.==
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The line below this paragraph, containing "STRUCTURE_1ocs", creates the "Structure Box" on the page.
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<StructureSection load='1ocs' size='340' side='right'caption='[[1ocs]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ocs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_1ocs| PDB=1ocs | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocs OCA], [https://pdbe.org/1ocs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocs RCSB], [https://www.ebi.ac.uk/pdbsum/1ocs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SNX3_YEAST SNX3_YEAST] Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).<ref>PMID:9456318</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ocs ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE YEAST PX-DOAMIN PROTEIN GRD19P (SORTING NEXIN3) COMPLEXED TO PHOSPHATIDYLINOSYTOL-3-PHOSPHATE.===
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==See Also==
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*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_14514667}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 14514667 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_14514667}}
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==About this Structure==
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1OCS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCS OCA].
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==Reference==
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Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate., Zhou CZ, de La Sierra-Gallay IL, Quevillon-Cheruel S, Collinet B, Minard P, Blondeau K, Henckes G, Aufrere R, Leulliot N, Graille M, Sorel I, Savarin P, de la Torre F, Poupon A, Janin J, van Tilbeurgh H, J Biol Chem. 2003 Dec 12;278(50):50371-6. Epub 2003 Sep 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14514667 14514667]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Aufrere R]]
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[[Category: Aufrere, R.]]
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[[Category: Blondeau K]]
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[[Category: Blondeau, K.]]
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[[Category: Cheruel S]]
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[[Category: Cheruel, S.]]
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[[Category: Collinet B]]
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[[Category: Collinet, B.]]
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[[Category: De La Torre F]]
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[[Category: Graille, M.]]
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[[Category: Graille M]]
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[[Category: Henkes, G.]]
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[[Category: Henkes G]]
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[[Category: Janin, J.]]
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[[Category: Janin J]]
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[[Category: Leulliot, N.]]
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[[Category: Leulliot N]]
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[[Category: Minard, P.]]
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[[Category: Li De La Sierra-Gallay I]]
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[[Category: Poupon, A.]]
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[[Category: Minard P]]
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[[Category: Savarin, P.]]
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[[Category: Poupon A]]
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[[Category: Sierra-Gallay, I Li De La.]]
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[[Category: Savarin P]]
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[[Category: Sorel, I.]]
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[[Category: Sorel I]]
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[[Category: Tilbeurgh, H Van.]]
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[[Category: Van Tilbeurgh H]]
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[[Category: Torre, F De La.]]
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[[Category: Zhou CZ]]
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[[Category: Zhou, C Z.]]
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[[Category: Px-domain]]
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[[Category: Sorting nexin]]
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[[Category: Yeast protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:45:08 2008''
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Current revision

Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.

PDB ID 1ocs

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