1ti3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:12, 22 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1ti3.png|left|200px]]
 
-
<!--
+
==Solution structure of the Thioredoxin h1 from poplar, a CPPC active site variant==
-
The line below this paragraph, containing "STRUCTURE_1ti3", creates the "Structure Box" on the page.
+
<StructureSection load='1ti3' size='340' side='right'caption='[[1ti3]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ti3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Populus_tremula Populus tremula]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TI3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ti3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ti3 OCA], [https://pdbe.org/1ti3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ti3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ti3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ti3 ProSAT]</span></td></tr>
-
{{STRUCTURE_1ti3| PDB=1ti3 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q8S3L3_POPPZ Q8S3L3_POPPZ]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ti/1ti3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ti3 ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Assignment of heteronuclear and homonuclear multidimensional NMR spectra permits determination of the first three-dimensional solution structure of a higher-plant thioredoxin h. The collection of 1906 distance restraints, 137 TALOS-derived dihedral restraints, and 66 hydrogen bonds was used in the restrained molecular dynamics protocol to calculate the structure of the reduced form of thioredoxin h1 from poplar with an atomic rmsd of 0.60 +/- 0.12 A. This enzyme exhibits an unusual active site with the sequence WCPPC and original properties in terms of stability and specificity. Compared to other known thioredoxin structures, thioredoxin h1 from poplar adopts the classical "Trx fold". Its atypical active site possesses a conformation similar to that of other common thioredoxins but appears to be more rigid. Moreover, the hydrogen bond network, stabilizing the in-core beta-sheet, is tighter than in Chlamydomonas reinhardtii, explaining the difference in thermostability.
-
===Solution structure of the Thioredoxin h1 from poplar, a CPPC active site variant===
+
Solution structure of a natural CPPC active site variant, the reduced form of thioredoxin h1 from poplar.,Coudevylle N, Thureau A, Hemmerlin C, Gelhaye E, Jacquot JP, Cung MT Biochemistry. 2005 Feb 15;44(6):2001-8. PMID:15697225<ref>PMID:15697225</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 1ti3" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_15697225}}, adds the Publication Abstract to the page
+
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 15697225 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_15697225}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
1TI3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Populus_tremula Populus tremula]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TI3 OCA].
+
-
 
+
-
==Reference==
+
-
Solution structure of a natural CPPC active site variant, the reduced form of thioredoxin h1 from poplar., Coudevylle N, Thureau A, Hemmerlin C, Gelhaye E, Jacquot JP, Cung MT, Biochemistry. 2005 Feb 15;44(6):2001-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15697225 15697225]
+
[[Category: Populus tremula]]
[[Category: Populus tremula]]
-
[[Category: Single protein]]
+
[[Category: Coudevylle N]]
-
[[Category: Coudevylle, N.]]
+
[[Category: Cung MT]]
-
[[Category: Cung, M T.]]
+
[[Category: Gelhaye E]]
-
[[Category: Gelhaye, E.]]
+
[[Category: Hemmerlin C]]
-
[[Category: Hemmerlin, C.]]
+
[[Category: Jacquot JP]]
-
[[Category: Jacquot, J P.]]
+
[[Category: Thureau A]]
-
[[Category: Thureau, A.]]
+
-
[[Category: Nmr]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Thioredoxin]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:08:15 2008''
+

Current revision

Solution structure of the Thioredoxin h1 from poplar, a CPPC active site variant

PDB ID 1ti3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ti3"
Personal tools