1pem

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{{Seed}}
 
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[[Image:1pem.png|left|200px]]
 
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==Ribonucleotide Reductase Protein R1E from Salmonella typhimurium==
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The line below this paragraph, containing "STRUCTURE_1pem", creates the "Structure Box" on the page.
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<StructureSection load='1pem' size='340' side='right'caption='[[1pem]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pem]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PEM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pem OCA], [https://pdbe.org/1pem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pem RCSB], [https://www.ebi.ac.uk/pdbsum/1pem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pem ProSAT]</span></td></tr>
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{{STRUCTURE_1pem| PDB=1pem | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIR3_SALTY RIR3_SALTY] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1E contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pe/1pem_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pem ConSurf].
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<div style="clear:both"></div>
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===Ribonucleotide Reductase Protein R1E from Salmonella typhimurium===
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==See Also==
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12818204}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12818204 is the PubMed ID number.
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Eklund H]]
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{{ABSTRACT_PUBMED_12818204}}
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[[Category: Eliasson R]]
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[[Category: Farnegardh M]]
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==About this Structure==
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[[Category: Jordan A]]
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1PEM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PEM OCA].
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[[Category: Uhlin U]]
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[[Category: Uppsten M]]
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==Reference==
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Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors., Uppsten M, Farnegardh M, Jordan A, Eliasson R, Eklund H, Uhlin U, J Mol Biol. 2003 Jun 27;330(1):87-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12818204 12818204]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Salmonella typhimurium]]
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[[Category: Single protein]]
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[[Category: Eklund, H.]]
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[[Category: Eliasson, R.]]
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[[Category: Farnegardh, M.]]
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[[Category: Jordan, A.]]
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[[Category: Uhlin, U.]]
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[[Category: Uppsten, M.]]
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[[Category: 10 stranded alpha/beta barrel]]
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[[Category: Datp]]
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[[Category: Protein-specificity-effector complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:21:19 2008''
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Current revision

Ribonucleotide Reductase Protein R1E from Salmonella typhimurium

PDB ID 1pem

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