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1lep

From Proteopedia

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{{Seed}}
 
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[[Image:1lep.png|left|200px]]
 
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==THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE==
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The line below this paragraph, containing "STRUCTURE_1lep", creates the "Structure Box" on the page.
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<StructureSection load='1lep' size='340' side='right'caption='[[1lep]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1lep]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LEP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lep OCA], [https://pdbe.org/1lep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lep RCSB], [https://www.ebi.ac.uk/pdbsum/1lep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lep ProSAT]</span></td></tr>
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{{STRUCTURE_1lep| PDB=1lep | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CH10_MYCLE CH10_MYCLE] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/le/1lep_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lep ConSurf].
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<div style="clear:both"></div>
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===THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE===
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==See Also==
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*[[Chaperonin 3D structures|Chaperonin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8539620}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8539620 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8539620}}
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==About this Structure==
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1LEP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LEP OCA].
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==Reference==
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Structure of the heat shock protein chaperonin-10 of Mycobacterium leprae., Mande SC, Mehra V, Bloom BR, Hol WG, Science. 1996 Jan 12;271(5246):203-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8539620 8539620]
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[[Category: Mycobacterium leprae]]
[[Category: Mycobacterium leprae]]
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[[Category: Single protein]]
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[[Category: Hol WGJ]]
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[[Category: Hol, W G.J.]]
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[[Category: Mande SC]]
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[[Category: Mande, S C.]]
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[[Category: Antigen]]
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[[Category: Chaperone]]
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[[Category: Heat shock]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:22:06 2008''
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Current revision

THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE

PDB ID 1lep

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