1q08

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{{Seed}}
 
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[[Image:1q08.png|left|200px]]
 
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==Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121)==
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The line below this paragraph, containing "STRUCTURE_1q08", creates the "Structure Box" on the page.
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<StructureSection load='1q08' size='340' side='right'caption='[[1q08]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q08 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1q08| PDB=1q08 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q08 OCA], [https://pdbe.org/1q08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q08 RCSB], [https://www.ebi.ac.uk/pdbsum/1q08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q08 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121)===
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== Function ==
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[https://www.uniprot.org/uniprot/ZNTR_ECOLI ZNTR_ECOLI] Zinc-responsive transcriptional regulator of zntA.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12958362 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q0/1q08_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12958362}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1Q08 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q08 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q08 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR., Changela A, Chen K, Xue Y, Holschen J, Outten CE, O'Halloran TV, Mondragon A, Science. 2003 Sep 5;301(5638):1383-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12958362 12958362]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Changela, A.]]
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[[Category: Changela A]]
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[[Category: Chen, K.]]
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[[Category: Chen K]]
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[[Category: Halloran, T V.O.]]
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[[Category: Holschen J]]
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[[Category: Holschen, J.]]
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[[Category: Mondragon A]]
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[[Category: Mondragon, A.]]
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[[Category: O'Halloran TV]]
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[[Category: Outten, C E.]]
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[[Category: Outten CE]]
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[[Category: Xue, Y.]]
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[[Category: Xue Y]]
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[[Category: Merr family transcriptional regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:22:17 2008''
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Current revision

Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121)

PDB ID 1q08

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