2fh9

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{{Seed}}
 
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[[Image:2fh9.png|left|200px]]
 
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==Structure and dimerization of the kinase domain from yeast Snf1==
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The line below this paragraph, containing "STRUCTURE_2fh9", creates the "Structure Box" on the page.
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<StructureSection load='2fh9' size='340' side='right'caption='[[2fh9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fh9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FH9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fh9 OCA], [https://pdbe.org/2fh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fh9 RCSB], [https://www.ebi.ac.uk/pdbsum/2fh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fh9 ProSAT]</span></td></tr>
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{{STRUCTURE_2fh9| PDB=2fh9 | SCENE= }}
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</table>
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== Function ==
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===Structure and dimerization of the kinase domain from yeast Snf1===
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[https://www.uniprot.org/uniprot/SNF1_YEAST SNF1_YEAST] Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters.<ref>PMID:15719021</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16531232 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/2fh9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16531232}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fh9 ConSurf].
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2FH9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FH9 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family., Nayak V, Zhao K, Wyce A, Schwartz MF, Lo WS, Berger SL, Marmorstein R, Structure. 2006 Mar;14(3):477-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16531232 16531232]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Nayak V]]
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[[Category: Nayak, V.]]
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[[Category: Dimer]]
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[[Category: Kinase domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:48:06 2008''
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Current revision

Structure and dimerization of the kinase domain from yeast Snf1

PDB ID 2fh9

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