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2rkp

From Proteopedia

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#REDIRECT [[3h30]] This PDB entry is obsolete and replaced by 3h30
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[[Image:2rkp.png|left|200px]]
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The line below this paragraph, containing "STRUCTURE_2rkp", creates the "Structure Box" on the page.
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{{STRUCTURE_2rkp| PDB=2rkp | SCENE= }}
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===Crystal structure of the catalytic subunit of human protein kinase CK2 with 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole===
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{{ABSTRACT_PUBMED_18291315}}
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==About this Structure==
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2RKP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKP OCA].
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==Reference==
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The CK2alpha/CK2beta Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules., Raaf J, Brunstein E, Issinger OG, Niefind K, Chem Biol. 2008 Feb;15(2):111-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18291315 18291315]
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Evolved to be active: sulfate ions define substrate recognition sites of CK2alpha and emphasise its exceptional role within the CMGC family of eukaryotic protein kinases., Niefind K, Yde CW, Ermakova I, Issinger OG, J Mol Biol. 2007 Jul 13;370(3):427-38. Epub 2007 May 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17524418 17524418]
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Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit., Ermakova I, Boldyreff B, Issinger OG, Niefind K, J Mol Biol. 2003 Jul 25;330(5):925-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12860116 12860116]
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
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[[Category: Issinger, O G.]]
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[[Category: Niefind, K.]]
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[[Category: Raaf, J.]]
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[[Category: Allosteric binding site]]
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[[Category: Atp-binding]]
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[[Category: Drb]]
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[[Category: Eukaryotic protein kinase fold]]
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[[Category: Human ck2alpha]]
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[[Category: Nucleotide-binding]]
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[[Category: Protein kinase ck2]]
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[[Category: Protein kinase inhibitor complex]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Wnt signaling pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:09:20 2008''
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Current revision

  1. REDIRECT 3h30 This PDB entry is obsolete and replaced by 3h30

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