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1lps

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(New page: 200px<br /><applet load="1lps" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lps, resolution 2.18&Aring;" /> '''A STRUCTURAL BASIS F...)
Current revision (08:26, 10 April 2024) (edit) (undo)
 
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[[Image:1lps.jpg|left|200px]]<br /><applet load="1lps" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1lps, resolution 2.18&Aring;" />
 
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'''A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES'''<br />
 
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==About this Structure==
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==A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES==
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1LPS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with NAG, CA and MPC as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LPS OCA].
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<StructureSection load='1lps' size='340' side='right'caption='[[1lps]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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[[Category: Single protein]]
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== Structural highlights ==
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[[Category: Triacylglycerol lipase]]
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<table><tr><td colspan='2'>[[1lps]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Diutina_rugosa Diutina rugosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LPS FirstGlance]. <br>
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[[Category: Cygler, M.C.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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[[Category: Grochulski, P.G.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPC:(1S)-MENTHYL+HEXYL+PHOSPHONATE+GROUP'>MPC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: CA]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lps OCA], [https://pdbe.org/1lps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lps RCSB], [https://www.ebi.ac.uk/pdbsum/1lps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lps ProSAT]</span></td></tr>
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[[Category: MPC]]
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</table>
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[[Category: NAG]]
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== Function ==
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[[Category: hydrolase (carboxylic esterase)]]
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[https://www.uniprot.org/uniprot/LIP1_DIURU LIP1_DIURU]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lps_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lps ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 20:46:11 2007''
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==See Also==
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*[[Lipase 3D Structures|Lipase 3D Structures]]
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__TOC__
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</StructureSection>
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[[Category: Diutina rugosa]]
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[[Category: Large Structures]]
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[[Category: Cygler MC]]
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[[Category: Grochulski PG]]

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A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES

PDB ID 1lps

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