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3d6v

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{{Seed}}
 
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[[Image:3d6v.png|left|200px]]
 
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==Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase==
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The line below this paragraph, containing "STRUCTURE_3d6v", creates the "Structure Box" on the page.
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<StructureSection load='3d6v' size='340' side='right'caption='[[3d6v]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d6v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2q1i 2q1i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D6V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=TFQ:4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE'>TFQ</scene></td></tr>
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{{STRUCTURE_3d6v| PDB=3d6v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d6v OCA], [https://pdbe.org/3d6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d6v RCSB], [https://www.ebi.ac.uk/pdbsum/3d6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d6v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYY_METJA SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/3d6v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d6v ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase===
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3D6V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2q1i 2q1i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D6V OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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A genetically encoded diazirine photocrosslinker in Escherichia coli., Tippmann EM, Liu W, Summerer D, Mack AV, Schultz PG, Chembiochem. 2007 Dec 17;8(18):2210-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18000916 18000916]
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[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Single protein]]
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[[Category: Liu W]]
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[[Category: Tyrosine--tRNA ligase]]
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[[Category: Mack AV]]
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[[Category: Liu, W.]]
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[[Category: Schultz PG]]
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[[Category: Mack, A V.]]
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[[Category: Tippmann E]]
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[[Category: Schultz, P G.]]
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[[Category: Tippmann, E.]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
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[[Category: Photocrosslinking unnatural amino acid]]
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[[Category: Protein biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:18:22 2008''
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Current revision

Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase

PDB ID 3d6v

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