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2i4t

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{{Seed}}
 
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[[Image:2i4t.png|left|200px]]
 
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==Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A==
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The line below this paragraph, containing "STRUCTURE_2i4t", creates the "Structure Box" on the page.
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<StructureSection load='2i4t' size='340' side='right'caption='[[2i4t]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2i4t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichomonas_vaginalis Trichomonas vaginalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I4T FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.74&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UA2:3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R'>UA2</scene></td></tr>
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{{STRUCTURE_2i4t| PDB=2i4t | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i4t OCA], [https://pdbe.org/2i4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i4t RCSB], [https://www.ebi.ac.uk/pdbsum/2i4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i4t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A2E7Y6_TRIV3 A2E7Y6_TRIV3]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i4/2i4t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i4t ConSurf].
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<div style="clear:both"></div>
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===Crystal stucture of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A===
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==See Also==
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*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17223688}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 17223688 is the PubMed ID number.
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[[Category: Trichomonas vaginalis]]
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[[Category: Almo SC]]
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{{ABSTRACT_PUBMED_17223688}}
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[[Category: Rinaldo-Matthis A]]
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[[Category: Schramm VL]]
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==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4T OCA].
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==Reference==
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Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues., Rinaldo-Matthis A, Wing C, Ghanem M, Deng H, Wu P, Gupta A, Tyler PC, Evans GB, Furneaux RH, Almo SC, Wang CC, Schramm VL, Biochemistry. 2007 Jan 23;46(3):659-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17223688 17223688]
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[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Almo, S C.]]
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[[Category: Rinaldo-Matthis, A.]]
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[[Category: Schramm, V L.]]
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[[Category: Purine nucleoside phosphorylase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:21:49 2008''
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Current revision

Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A

PDB ID 2i4t

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