1lqk
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1lqk" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lqk, resolution 1.35Å" /> '''High Resolution Stru...) |
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| - | [[Image:1lqk.gif|left|200px]]<br /><applet load="1lqk" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1lqk, resolution 1.35Å" /> | ||
| - | '''High Resolution Structure of Fosfomycin Resistance Protein A (FosA)'''<br /> | ||
| - | == | + | ==High Resolution Structure of Fosfomycin Resistance Protein A (FosA)== |
| - | + | <StructureSection load='1lqk' size='340' side='right'caption='[[1lqk]], [[Resolution|resolution]] 1.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1lqk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQK FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqk OCA], [https://pdbe.org/1lqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lqk RCSB], [https://www.ebi.ac.uk/pdbsum/1lqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FOSA_PSEAE FOSA_PSEAE] Metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lqk_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lqk ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
| - | + | [[Category: Armstrong RN]] | |
| - | [[Category: Armstrong | + | [[Category: Newcomer ME]] |
| - | [[Category: Newcomer | + | [[Category: Pharris RE]] |
| - | [[Category: Pharris | + | [[Category: Rife CL]] |
| - | [[Category: Rife | + | |
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Current revision
High Resolution Structure of Fosfomycin Resistance Protein A (FosA)
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