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1y79

From Proteopedia

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{{Seed}}
 
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[[Image:1y79.png|left|200px]]
 
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<!--
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==Crystal Structure of the E.coli Dipeptidyl Carboxypeptidase Dcp in Complex with a Peptidic Inhibitor==
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The line below this paragraph, containing "STRUCTURE_1y79", creates the "Structure Box" on the page.
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<StructureSection load='1y79' size='340' side='right'caption='[[1y79]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1y79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y79 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1y79| PDB=1y79 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y79 OCA], [https://pdbe.org/1y79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y79 RCSB], [https://www.ebi.ac.uk/pdbsum/1y79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y79 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of the E.coli Dipeptidyl Carboxypeptidase Dcp in Complex with a Peptidic Inhibitor===
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== Function ==
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[https://www.uniprot.org/uniprot/DCP_ECOLI DCP_ECOLI] Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15876371}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15876371 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y7/1y79_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15876371}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1Y79 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y79 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y79 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of the E. coli dipeptidyl carboxypeptidase Dcp: further indication of a ligand-dependent hinge movement mechanism., Comellas-Bigler M, Lang R, Bode W, Maskos K, J Mol Biol. 2005 May 27;349(1):99-112. Epub 2005 Mar 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15876371 15876371]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Peptidyl-dipeptidase Dcp]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Bode W]]
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[[Category: Bode, W.]]
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[[Category: Comellas-Bigler M]]
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[[Category: Comellas-Bigler, M.]]
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[[Category: Lang R]]
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[[Category: Lang, R.]]
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[[Category: Maskos K]]
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[[Category: Maskos, K.]]
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[[Category: Ace]]
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[[Category: Carboxypeptidase]]
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[[Category: Dcp]]
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[[Category: Hinge bending]]
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[[Category: Neurolysin]]
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[[Category: Peptidyl dipeptidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:50:36 2008''
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Current revision

Crystal Structure of the E.coli Dipeptidyl Carboxypeptidase Dcp in Complex with a Peptidic Inhibitor

PDB ID 1y79

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