1lv3

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(New page: 200px<br /><applet load="1lv3" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lv3" /> '''Solution NMR Structure of Zinc Finger Protei...)
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[[Image:1lv3.gif|left|200px]]<br /><applet load="1lv3" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1lv3" />
 
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'''Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.'''<br />
 
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==About this Structure==
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==Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.==
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1LV3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA].
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<StructureSection load='1lv3' size='340' side='right'caption='[[1lv3]]' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[1lv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV3 FirstGlance]. <br>
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NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins., Ramelot TA, Cort JR, Yee AA, Semesi A, Edwards AM, Arrowsmith CH, Kennedy MA, Proteins. 2002 Nov 1;49(2):289-93. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12211008 12211008]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv3 OCA], [https://pdbe.org/1lv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1lv3 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YACG_ECOLI YACG_ECOLI] Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<ref>PMID:18586829</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv3 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C.H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Cort, J.R.]]
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[[Category: Cort JR]]
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[[Category: Edwards, A.M.]]
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[[Category: Edwards AM]]
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[[Category: Kennedy, M.A.]]
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[[Category: Kennedy MA]]
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[[Category: NESG, Northeast.Structural.Genomics.Consortium.]]
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[[Category: Ramelot TA]]
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[[Category: Ramelot, T.A.]]
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[[Category: Semesi A]]
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[[Category: Semesi, A.]]
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[[Category: Yee AA]]
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[[Category: Yee, A.A.]]
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[[Category: ZN]]
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[[Category: antiparallel beta strand and alpha helix]]
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[[Category: c4 tetrahedral zn+2]]
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[[Category: et92]]
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[[Category: nesg project]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: rubredoxin knuckle]]
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[[Category: structural genomics]]
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[[Category: zinc finger]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 20:54:41 2007''
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Current revision

Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.

PDB ID 1lv3

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