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2ffz

From Proteopedia

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{{Seed}}
 
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[[Image:2ffz.png|left|200px]]
 
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==Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants==
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The line below this paragraph, containing "STRUCTURE_2ffz", creates the "Structure Box" on the page.
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<StructureSection load='2ffz' size='340' side='right'caption='[[2ffz]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ffz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FFZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2ffz| PDB=2ffz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ffz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffz OCA], [https://pdbe.org/2ffz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ffz RCSB], [https://www.ebi.ac.uk/pdbsum/2ffz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHLC_BACCE PHLC_BACCE] Required, with sphingomyelinase, to effect target cell lysis (hemolysis).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/2ffz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ffz ConSurf].
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<div style="clear:both"></div>
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===Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants===
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==See Also==
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*[[Phospholipase C|Phospholipase C]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17324372}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17324372 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17324372}}
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==About this Structure==
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2FFZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFZ OCA].
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==Reference==
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Structural studies examining the substrate specificity profiles of PC-PLC(Bc) protein variants., Benfield AP, Goodey NM, Phillips LT, Martin SF, Arch Biochem Biophys. 2007 Apr 1;460(1):41-7. Epub 2007 Feb 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17324372 17324372]
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[[Category: Bacillus cereus]]
[[Category: Bacillus cereus]]
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[[Category: Phospholipase C]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Antikainen NM]]
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[[Category: Antikainen, N M.]]
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[[Category: Benfield AB]]
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[[Category: Benfield, A B.]]
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[[Category: Martin SF]]
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[[Category: Martin, S F.]]
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[[Category: Pc-plcbc protein variant]]
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[[Category: Substrate specificity]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:48:25 2008''
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Current revision

Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants

PDB ID 2ffz

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