2cad

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{{Seed}}
 
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[[Image:2cad.png|left|200px]]
 
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<!--
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==NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 2F, 2X and 2I sites.==
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The line below this paragraph, containing "STRUCTURE_2cad", creates the "Structure Box" on the page.
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<StructureSection load='2cad' size='340' side='right'caption='[[2cad]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2cad]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CAD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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{{STRUCTURE_2cad| PDB=2cad | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cad OCA], [https://pdbe.org/2cad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cad RCSB], [https://www.ebi.ac.uk/pdbsum/2cad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cad ProSAT]</span></td></tr>
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</table>
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===NIKR FROM HELICOBACTER PYLORI IN CLOSED TRANS-CONFORMATION AND NICKEL BOUND TO 2F, 2X AND 2I SITES.===
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== Function ==
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[https://www.uniprot.org/uniprot/NIKR_HELPY NIKR_HELPY] Transcriptional regulator (Potential).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16872629}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16872629 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2cad_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16872629}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2CAD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CAD OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cad ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural basis of the nickel response in Helicobacter pylori: crystal structures of HpNikR in Apo and nickel-bound states., Dian C, Schauer K, Kapp U, McSweeney SM, Labigne A, Terradot L, J Mol Biol. 2006 Aug 25;361(4):715-30. Epub 2006 Jul 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16872629 16872629]
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</StructureSection>
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[[Category: Helicobacter pylori]]
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[[Category: Helicobacter pylori 26695]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Dian, C.]]
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[[Category: Dian C]]
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[[Category: Kapp, U.]]
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[[Category: Kapp U]]
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[[Category: Labigne, A.]]
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[[Category: Labigne A]]
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[[Category: Mcsweeney, S M.]]
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[[Category: McSweeney SM]]
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[[Category: Schauer, K.]]
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[[Category: Schauer K]]
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[[Category: Terradot, L.]]
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[[Category: Terradot L]]
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[[Category: Acidic-adaptive response]]
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[[Category: Dna-binding]]
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[[Category: Hypothetical protein]]
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[[Category: Metal-binding]]
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[[Category: Nickel]]
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[[Category: Nickel uptake]]
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[[Category: Ribbon-helix-helix]]
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[[Category: Transcription regulator]]
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[[Category: Transcriptional regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:32:17 2008''
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Current revision

NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 2F, 2X and 2I sites.

PDB ID 2cad

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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