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1tfr

From Proteopedia

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{{Seed}}
 
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[[Image:1tfr.png|left|200px]]
 
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<!--
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==RNASE H FROM BACTERIOPHAGE T4==
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The line below this paragraph, containing "STRUCTURE_1tfr", creates the "Structure Box" on the page.
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<StructureSection load='1tfr' size='340' side='right'caption='[[1tfr]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tfr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TFR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1tfr| PDB=1tfr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tfr OCA], [https://pdbe.org/1tfr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tfr RCSB], [https://www.ebi.ac.uk/pdbsum/1tfr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tfr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNH_BPT4 RNH_BPT4] 5' to 3' exonuclease that removes the pentamer RNA primers from DNA chains initiated by the T4 primase-helicase.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tf/1tfr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tfr ConSurf].
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<div style="clear:both"></div>
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===RNASE H FROM BACTERIOPHAGE T4===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8674116}}, adds the Publication Abstract to the page
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[[Category: Escherichia virus T4]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8674116 is the PubMed ID number.
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[[Category: Large Structures]]
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-->
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[[Category: Hyde CC]]
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{{ABSTRACT_PUBMED_8674116}}
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[[Category: Mueser TC]]
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[[Category: Nossal NG]]
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==About this Structure==
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1TFR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFR OCA].
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==Reference==
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Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins., Mueser TC, Nossal NG, Hyde CC, Cell. 1996 Jun 28;85(7):1101-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8674116 8674116]
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[[Category: Enterobacteria phage t4]]
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[[Category: Ribonuclease H]]
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[[Category: Single protein]]
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[[Category: Hyde, C C.]]
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[[Category: Mueser, T C.]]
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[[Category: Nossal, N G.]]
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[[Category: 5u-3u exonuclease]]
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[[Category: Dna:dna]]
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[[Category: Magnesium-containing]]
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[[Category: Metal-dependent]]
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[[Category: Rna:rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:01:08 2008''
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Current revision

RNASE H FROM BACTERIOPHAGE T4

PDB ID 1tfr

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