This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1sk0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:14, 3 April 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1sk0.png|left|200px]]
 
-
<!--
+
==ARSENATE REDUCTASE R60A MUTANT +0.4M ARSENITE FROM E. COLI==
-
The line below this paragraph, containing "STRUCTURE_1sk0", creates the "Structure Box" on the page.
+
<StructureSection load='1sk0' size='340' side='right'caption='[[1sk0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1sk0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SK0 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=CZ2:S-(DIHYDROXYARSINO)CYSTEINE'>CZ2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TAS:TRIHYDROXYARSENITE(III)'>TAS</scene></td></tr>
-
{{STRUCTURE_1sk0| PDB=1sk0 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sk0 OCA], [https://pdbe.org/1sk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sk0 RCSB], [https://www.ebi.ac.uk/pdbsum/1sk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sk0 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ARSC1_ECOLX ARSC1_ECOLX] Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sk/1sk0_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sk0 ConSurf].
 +
<div style="clear:both"></div>
-
===ARSENATE REDUCTASE R60A MUTANT +0.4M ARSENITE FROM E. COLI===
+
==See Also==
-
 
+
*[[Arsenate reductase 3D structures|Arsenate reductase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15295115}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 15295115 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15295115}}
+
-
 
+
-
==About this Structure==
+
-
1SK0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SK0 OCA].
+
-
 
+
-
==Reference==
+
-
Arginine 60 in the ArsC arsenate reductase of E. coli plasmid R773 determines the chemical nature of the bound As(III) product., DeMel S, Shi J, Martin P, Rosen BP, Edwards BF, Protein Sci. 2004 Sep;13(9):2330-40. Epub 2004 Aug 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15295115 15295115]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Demel, S.]]
+
[[Category: Demel S]]
-
[[Category: Edwards, B F.]]
+
[[Category: Edwards BF]]
-
[[Category: Arsc]]
+
-
[[Category: Arsenate]]
+
-
[[Category: Arsenite]]
+
-
[[Category: Reductase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:04:39 2008''
+

Current revision

ARSENATE REDUCTASE R60A MUTANT +0.4M ARSENITE FROM E. COLI

PDB ID 1sk0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1sk0"
Personal tools