1qcy

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{{Seed}}
 
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[[Image:1qcy.png|left|200px]]
 
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==THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1==
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The line below this paragraph, containing "STRUCTURE_1qcy", creates the "Structure Box" on the page.
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<StructureSection load='1qcy' size='340' side='right'caption='[[1qcy]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QCY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1qcy| PDB=1qcy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qcy OCA], [https://pdbe.org/1qcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qcy RCSB], [https://www.ebi.ac.uk/pdbsum/1qcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qcy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ITA1_HUMAN ITA1_HUMAN] Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qc/1qcy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qcy ConSurf].
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<div style="clear:both"></div>
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===THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1===
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==See Also==
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*[[Integrin 3D structures|Integrin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_14660600}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 14660600 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14660600}}
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==About this Structure==
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1QCY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QCY OCA].
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==Reference==
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Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1., Nymalm Y, Puranen JS, Nyholm TK, Kapyla J, Kidron H, Pentikainen OT, Airenne TT, Heino J, Slotte JP, Johnson MS, Salminen TA, J Biol Chem. 2004 Feb 27;279(9):7962-70. Epub 2003 Dec 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14660600 14660600]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Heino, J.]]
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[[Category: Heino J]]
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[[Category: Johnson, M S.]]
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[[Category: Johnson MS]]
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[[Category: Kaepylae, J.]]
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[[Category: Kaepylae J]]
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[[Category: Kankare, J A.]]
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[[Category: Kankare JA]]
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[[Category: Nymalm, Y.]]
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[[Category: Nymalm Y]]
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[[Category: Salminen, T A.]]
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[[Category: Salminen TA]]
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[[Category: Dinucleotide binding fold]]
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[[Category: Rossman fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:18:20 2008''
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Current revision

THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1

PDB ID 1qcy

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