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2ipc

From Proteopedia

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{{Seed}}
 
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[[Image:2ipc.png|left|200px]]
 
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==Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer==
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The line below this paragraph, containing "STRUCTURE_2ipc", creates the "Structure Box" on the page.
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<StructureSection load='2ipc' size='340' side='right'caption='[[2ipc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ipc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IPC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ipc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ipc OCA], [https://pdbe.org/2ipc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ipc RCSB], [https://www.ebi.ac.uk/pdbsum/2ipc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ipc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ipc TOPSAN]</span></td></tr>
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{{STRUCTURE_2ipc| PDB=2ipc | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SECA_THET8 SECA_THET8] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.[HAMAP-Rule:MF_01382]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ip/2ipc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ipc ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer===
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==See Also==
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*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
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*[[SecA|SecA]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_17059823}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 17059823 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Thermus thermophilus HB8]]
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{{ABSTRACT_PUBMED_17059823}}
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[[Category: Ito K]]
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[[Category: Kimura Y]]
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==About this Structure==
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[[Category: Mori H]]
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2IPC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPC OCA].
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[[Category: Tahirov TH]]
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[[Category: Tsukazaki T]]
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==Reference==
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[[Category: Vassylyev DG]]
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Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer., Vassylyev DG, Mori H, Vassylyeva MN, Tsukazaki T, Kimura Y, Tahirov TH, Ito K, J Mol Biol. 2006 Dec 1;364(3):248-58. Epub 2006 Sep 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17059823 17059823]
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[[Category: Vassylyeva MN]]
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[[Category: Single protein]]
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[[Category: Thermus thermophilus]]
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[[Category: Ito, K.]]
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[[Category: Kimura, Y.]]
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[[Category: Mori, H.]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Tahirov, T H.]]
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[[Category: Tsukazaki, T.]]
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[[Category: Vassylyev, D G.]]
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[[Category: Vassylyeva, M N.]]
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[[Category: Atpase]]
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[[Category: Nucleotide binding fold]]
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[[Category: Parallel dimer]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:27:17 2008''
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Current revision

Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer

PDB ID 2ipc

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