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1u00

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{{Seed}}
 
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[[Image:1u00.png|left|200px]]
 
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<!--
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==HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC==
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The line below this paragraph, containing "STRUCTURE_1u00", creates the "Structure Box" on the page.
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<StructureSection load='1u00' size='340' side='right'caption='[[1u00]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1u00]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U00 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u00 OCA], [https://pdbe.org/1u00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u00 RCSB], [https://www.ebi.ac.uk/pdbsum/1u00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u00 ProSAT]</span></td></tr>
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{{STRUCTURE_1u00| PDB=1u00 | SCENE= }}
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</table>
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== Function ==
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===HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC===
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[https://www.uniprot.org/uniprot/HSCA_ECOLI HSCA_ECOLI] Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.[HAMAP-Rule:MF_00679]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15351650}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15351650 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u00_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15351650}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u00 ConSurf].
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1U00 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U00 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of the molecular chaperone HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC., Cupp-Vickery JR, Peterson JC, Ta DT, Vickery LE, J Mol Biol. 2004 Sep 24;342(4):1265-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15351650 15351650]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Cupp-Vickery, J R.]]
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[[Category: Cupp-Vickery JR]]
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[[Category: Peterson, J C.]]
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[[Category: Peterson JC]]
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[[Category: Ta, D T.]]
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[[Category: Ta DT]]
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[[Category: Vickery, L E.]]
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[[Category: Vickery LE]]
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[[Category: Dnak]]
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[[Category: Hsc66]]
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[[Category: Hsca]]
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[[Category: Hsp70]]
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[[Category: Iscu]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:47:33 2008''
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Current revision

HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC

PDB ID 1u00

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