1swx

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{{Seed}}
 
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[[Image:1swx.png|left|200px]]
 
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==Crystal structure of a human glycolipid transfer protein in apo-form==
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The line below this paragraph, containing "STRUCTURE_1swx", creates the "Structure Box" on the page.
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<StructureSection load='1swx' size='340' side='right'caption='[[1swx]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1swx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SWX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEX:HEXANE'>HEX</scene></td></tr>
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{{STRUCTURE_1swx| PDB=1swx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1swx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1swx OCA], [https://pdbe.org/1swx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1swx RCSB], [https://www.ebi.ac.uk/pdbsum/1swx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1swx ProSAT]</span></td></tr>
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</table>
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===Crystal structure of a human glycolipid transfer protein in apo-form===
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== Function ==
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[https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15329726 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sw/1swx_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15329726}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1SWX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SWX OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1swx ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structural basis for glycosphingolipid transfer specificity., Malinina L, Malakhova ML, Teplov A, Brown RE, Patel DJ, Nature. 2004 Aug 26;430(7003):1048-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15329726 15329726]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Brown, R E.]]
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[[Category: Brown RE]]
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[[Category: Malakhova, M L.]]
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[[Category: Malakhova ML]]
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[[Category: Malinina, L.]]
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[[Category: Malinina L]]
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[[Category: Patel, D J.]]
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[[Category: Patel DJ]]
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[[Category: Teplov, A.]]
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[[Category: Teplov A]]
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[[Category: Glycosphingolipid intermembrane transfer protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:55:18 2008''
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Current revision

Crystal structure of a human glycolipid transfer protein in apo-form

PDB ID 1swx

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