1sz9

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{{Seed}}
 
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[[Image:1sz9.png|left|200px]]
 
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==The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model==
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The line below this paragraph, containing "STRUCTURE_1sz9", creates the "Structure Box" on the page.
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<StructureSection load='1sz9' size='340' side='right'caption='[[1sz9]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sz9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZ9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sz9 OCA], [https://pdbe.org/1sz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sz9 RCSB], [https://www.ebi.ac.uk/pdbsum/1sz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sz9 ProSAT]</span></td></tr>
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{{STRUCTURE_1sz9| PDB=1sz9 | SCENE= }}
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</table>
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== Function ==
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===The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model===
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[https://www.uniprot.org/uniprot/PCF11_YEAST PCF11_YEAST] Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Independently involved in RNA polymerase II transcript termination. Binds RNA. Seems to bridge RNA polymerase II and the native transcript and may be involved in dismantling the RNA polymerase II elongation complex.<ref>PMID:11344258</ref> <ref>PMID:15998810</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15241417 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1sz9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15241417}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sz9 ConSurf].
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1SZ9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZ9 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors., Meinhart A, Cramer P, Nature. 2004 Jul 8;430(6996):223-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15241417 15241417]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Cramer P]]
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[[Category: Cramer, P.]]
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[[Category: Meinhart A]]
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[[Category: Meinhart, A.]]
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[[Category: Arm repeat]]
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[[Category: Pcf11]]
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[[Category: Rna polymerase ii ctd interacting domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:38:54 2008''
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Current revision

The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model

PDB ID 1sz9

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