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1z3h

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{{Seed}}
 
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[[Image:1z3h.png|left|200px]]
 
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<!--
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==The exportin Cse1 in its cargo-free, cytoplasmic state==
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The line below this paragraph, containing "STRUCTURE_1z3h", creates the "Structure Box" on the page.
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<StructureSection load='1z3h' size='340' side='right'caption='[[1z3h]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1z3h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z3H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1z3h| PDB=1z3h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z3h OCA], [https://pdbe.org/1z3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z3h RCSB], [https://www.ebi.ac.uk/pdbsum/1z3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z3h ProSAT]</span></td></tr>
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</table>
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===The exportin Cse1 in its cargo-free, cytoplasmic state===
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== Function ==
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[https://www.uniprot.org/uniprot/CSE1_YEAST CSE1_YEAST] Export receptor for importin alpha (SRP1). Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm.<ref>PMID:9744791</ref> <ref>PMID:9857050</ref> <ref>PMID:9774694</ref> <ref>PMID:10394916</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15866177}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15866177 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/1z3h_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15866177}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1Z3H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3H OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z3h ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding., Cook A, Fernandez E, Lindner D, Ebert J, Schlenstedt G, Conti E, Mol Cell. 2005 Apr 29;18(3):355-67. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15866177 15866177]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Conti E]]
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[[Category: Conti, E.]]
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[[Category: Cook A]]
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[[Category: Cook, A.]]
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[[Category: Ebert J]]
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[[Category: Ebert, J.]]
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[[Category: Fernandez E]]
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[[Category: Fernandez, E.]]
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[[Category: Lindner D]]
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[[Category: Lindner, D.]]
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[[Category: Schlenstedt G]]
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[[Category: Schlenstedt, G.]]
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[[Category: Cse1]]
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[[Category: Exportin]]
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[[Category: Heat repeat]]
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[[Category: Nuclear transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:03:11 2008''
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Current revision

The exportin Cse1 in its cargo-free, cytoplasmic state

PDB ID 1z3h

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