1s2x

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[[Image:1s2x.png|left|200px]]
 
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==Crystal structure of Cag-Z from Helicobacter pylori==
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The line below this paragraph, containing "STRUCTURE_1s2x", creates the "Structure Box" on the page.
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<StructureSection load='1s2x' size='340' side='right'caption='[[1s2x]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1s2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S2X FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1s2x| PDB=1s2x | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s2x OCA], [https://pdbe.org/1s2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s2x RCSB], [https://www.ebi.ac.uk/pdbsum/1s2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s2x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9JMX9_HELPX Q9JMX9_HELPX]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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CagZ, a 23 kDa protein encoded by the cagZ gene (HP0526) of the cag pathogenicity island of Helicobacter pylori, has been cloned, over-expressed, purified and its three-dimensional structure determined. The protein consists of a single compact L-shaped domain, composed of seven alpha-helices including about 70% of the total residues. Three-dimensional homology searches did not reveal structural homologues, and CagZ can be considered representative of a new protein fold. The presence of a disordered C-terminal tail and the nature of the molecular surface suggest that CagZ may participate in the interaction of effector proteins with one or more components of the H.pylori type IV secretion system on the cytoplasmic side of the inner membrane.
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===Crystal structure of Cag-Z from Helicobacter pylori===
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Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system.,Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:15223328<ref>PMID:15223328</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_15223328}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1s2x" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15223328 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15223328}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1S2X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2X OCA].
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==Reference==
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Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system., Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G, J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15223328 15223328]
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[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Angelini, A.]]
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[[Category: Angelini A]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Cendron, L.]]
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[[Category: Cendron L]]
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[[Category: Seydel, A.]]
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[[Category: Seydel A]]
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[[Category: Zanotti, G.]]
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[[Category: Zanotti G]]
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[[Category: Cag pathogenicity island]]
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[[Category: Cag-z]]
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[[Category: Helicobacter pylori]]
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[[Category: Type iv secretion system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:08:12 2008''
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Current revision

Crystal structure of Cag-Z from Helicobacter pylori

PDB ID 1s2x

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