2pxg

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{{Seed}}
 
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[[Image:2pxg.png|left|200px]]
 
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==NMR Solution Structure of OmlA==
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The line below this paragraph, containing "STRUCTURE_2pxg", creates the "Structure Box" on the page.
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<StructureSection load='2pxg' size='340' side='right'caption='[[2pxg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_citri Xanthomonas citri]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PXG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pxg OCA], [https://pdbe.org/2pxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pxg RCSB], [https://www.ebi.ac.uk/pdbsum/2pxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pxg ProSAT]</span></td></tr>
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</table>
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{{STRUCTURE_2pxg| PDB=2pxg | SCENE= }}
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== Function ==
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[https://www.uniprot.org/uniprot/Q8PMB6_XANAC Q8PMB6_XANAC] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity).[HAMAP-Rule:MF_00925]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/px/2pxg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pxg ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The outer membrane lipoprotein A (OmlA) belongs to a family of bacterial small lipoproteins widely distributed across the beta and gamma proteobacteria. Although the role of numerous bacterial lipoproteins is known, the biological function of OmlA remains elusive. We found that in the citrus canker pathogen, Xanthomonas axonopodis pv. citri (X. citri), OmlA is coregulated with the ferric uptake regulator (Fur) and their expression is enhanced when X. citri is grown on citrus leaves, suggesting that these proteins are involved in plant-pathogen interaction. To gain insights into the function of OmlA, its conformational and dynamic features were determined by nuclear magnetic resonance. The protein has highly flexible N- and C- termini and a structurally well defined core composed of three beta-strands and two small alpha-helices, which pack against each other forming a two-layer alpha/beta scaffold. This protein fold resembles the domains of the beta-lactamase inhibitory protein BLIP, involved in protein-protein binding. In conclusion, the structure of OmlA does suggest that this protein may be implicated in protein-protein interactions required during X. citri infection. Proteins 2008. (c) 2008 Wiley-Liss, Inc.
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===NMR Solution Structure of OmlA===
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The solution structure of the outer membrane lipoprotein OmlA from Xanthomonas axonopodis pv. citri reveals a protein fold implicated in protein-protein interaction.,Vanini MM, Spisni A, Sforca ML, Pertinhez TA, Benedetti CE Proteins. 2008 Jan 10;. PMID:18186471<ref>PMID:18186471</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_18186471}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2pxg" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 18186471 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_18186471}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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2PXG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xanthomonas_axonopodis_pv._citri Xanthomonas axonopodis pv. citri]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PXG OCA].
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[[Category: Xanthomonas citri]]
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[[Category: Benedetti CE]]
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==Reference==
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[[Category: Pertinhez TA]]
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The solution structure of the outer membrane lipoprotein OmlA from Xanthomonas axonopodis pv. citri reveals a protein fold implicated in protein-protein interaction., Vanini MM, Spisni A, Sforca ML, Pertinhez TA, Benedetti CE, Proteins. 2008 Jan 10;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18186471 18186471]
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[[Category: Sforca ML]]
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[[Category: Single protein]]
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[[Category: Spisni A]]
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[[Category: Xanthomonas axonopodis pv. citri]]
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[[Category: Vanini MMT]]
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[[Category: Benedetti, C E.]]
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[[Category: Pertinhez, T A.]]
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[[Category: Sforca, M L.]]
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[[Category: Spisni, A.]]
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[[Category: Vanini, M M.T.]]
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[[Category: Membrane protein]]
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[[Category: Two layer alpha/beta plait]]
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[[Category: Two layer sandwich architecture]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:10:00 2008''
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Current revision

NMR Solution Structure of OmlA

PDB ID 2pxg

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