1zig

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{{Seed}}
 
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[[Image:1zig.png|left|200px]]
 
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==GAGA RNA TETRALOOP, NMR, 10 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1zig", creates the "Structure Box" on the page.
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<StructureSection load='1zig' size='340' side='right'caption='[[1zig]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zig]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZIG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zig OCA], [https://pdbe.org/1zig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zig RCSB], [https://www.ebi.ac.uk/pdbsum/1zig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zig ProSAT]</span></td></tr>
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{{STRUCTURE_1zig| PDB=1zig | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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RNA hairpin loops containing a GNRA consensus sequence are the most frequently occurring hairpins in a variety of prokaryotic and eukaryotic RNAs. These tetraloops play important functional roles in RNA folding, in RNA-RNA tertiary interactions and as protein binding sites. Homo and heteronuclear NMR spectroscopy have been used to determine the structures of the most abundant members of the GNRA tetraloop family: the GAGA, GCAA and GAAA loops closed by a C-G base pair. Analysis of the structures of these three hairpin loops reveals a network of heterogeneous hydrogen bonds. The loops contain a G-A base pair, a G base-phosphate hydrogen bond and several 2' OH-base hydrogen bonds. These intramolecular interactions and the extensive base stacking in the loop help explain the high thermodynamic stability and give insight into the diverse biological roles of the GNRA RNA hairpins.
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===GAGA RNA TETRALOOP, NMR, 10 STRUCTURES===
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A network of heterogeneous hydrogen bonds in GNRA tetraloops.,Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:9000624<ref>PMID:9000624</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_9000624}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1zig" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 9000624 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_9000624}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZIG OCA].
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[[Category: Heus HA]]
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[[Category: Jucker FM]]
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==Reference==
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[[Category: Moors E]]
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A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9000624 9000624]
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[[Category: Pardi A]]
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[[Category: Heus, H A.]]
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[[Category: Yip PF]]
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[[Category: Jucker, F M.]]
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[[Category: Moors, E.]]
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[[Category: Pardi, A.]]
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[[Category: Yip, P F.]]
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[[Category: Gnra]]
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[[Category: Hairpin]]
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[[Category: Ribonucleic acid]]
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[[Category: Rna]]
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[[Category: Tetraloop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:14:49 2008''
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Current revision

GAGA RNA TETRALOOP, NMR, 10 STRUCTURES

PDB ID 1zig

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