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1s6l

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{{Seed}}
 
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[[Image:1s6l.png|left|200px]]
 
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==Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system==
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The line below this paragraph, containing "STRUCTURE_1s6l", creates the "Structure Box" on the page.
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<StructureSection load='1s6l' size='340' side='right'caption='[[1s6l]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1s6l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S6L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s6l OCA], [https://pdbe.org/1s6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s6l RCSB], [https://www.ebi.ac.uk/pdbsum/1s6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s6l ProSAT]</span></td></tr>
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{{STRUCTURE_1s6l| PDB=1s6l | SCENE= }}
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</table>
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== Function ==
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===Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system===
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[https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15222745}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15222745 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s6/1s6l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15222745}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s6l ConSurf].
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1S6L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S6L OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system., Di Lello P, Benison GC, Valafar H, Pitts KE, Summers AO, Legault P, Omichinski JG, Biochemistry. 2004 Jul 6;43(26):8322-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15222745 15222745]
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1H, 15N, and 13C resonance assignment of the 23 kDa organomercurial lyase MerB in its free and mercury-bound forms., Di Lello P, Benison GC, Omichinski JG, Legault P, J Biomol NMR. 2004 Jul;29(3):457-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15213467 15213467]
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[[Category: Alkylmercury lyase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Benison, G C.]]
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[[Category: Benison GC]]
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[[Category: Legault, P.]]
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[[Category: Di Lello P]]
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[[Category: Lello, P Di.]]
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[[Category: Legault P]]
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[[Category: Omichinski, J G.]]
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[[Category: Omichinski JG]]
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[[Category: Pitts, K E.]]
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[[Category: Pitts KE]]
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[[Category: Summers, A O.]]
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[[Category: Summers AO]]
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[[Category: Valafar, H.]]
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[[Category: Valafar H]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:38:36 2008''
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Current revision

Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system

PDB ID 1s6l

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