1oxz

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{{Seed}}
 
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[[Image:1oxz.png|left|200px]]
 
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==Crystal Structure of the Human GGA1 GAT domain==
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The line below this paragraph, containing "STRUCTURE_1oxz", creates the "Structure Box" on the page.
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<StructureSection load='1oxz' size='340' side='right'caption='[[1oxz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1oxz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OXZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxz OCA], [https://pdbe.org/1oxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oxz RCSB], [https://www.ebi.ac.uk/pdbsum/1oxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oxz ProSAT]</span></td></tr>
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{{STRUCTURE_1oxz| PDB=1oxz | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of the Human GGA1 GAT domain===
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[https://www.uniprot.org/uniprot/GGA1_HUMAN GGA1_HUMAN] Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.<ref>PMID:11301005</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_12767220}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 12767220 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/1oxz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_12767220}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oxz ConSurf].
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1OXZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXZ OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of the human GGA1 GAT domain., Zhu G, Zhai P, He X, Terzyan S, Zhang R, Joachimiak A, Tang J, Zhang XC, Biochemistry. 2003 Jun 3;42(21):6392-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12767220 12767220]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: He, X.]]
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[[Category: He X]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Tang, J.]]
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[[Category: Tang J]]
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[[Category: Terzyan, S.]]
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[[Category: Terzyan S]]
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[[Category: Zhai, P.]]
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[[Category: Zhai P]]
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[[Category: Zhang, R.]]
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[[Category: Zhang R]]
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[[Category: Zhang, X C.]]
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[[Category: Zhang XC]]
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[[Category: Zhu, G.]]
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[[Category: Zhu G]]
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[[Category: Gat domain]]
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[[Category: Gga1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:39:25 2008''
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Current revision

Crystal Structure of the Human GGA1 GAT domain

PDB ID 1oxz

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OCA

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