1rkb

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{{Seed}}
 
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[[Image:1rkb.png|left|200px]]
 
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==The structure of adrenal gland protein AD-004==
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The line below this paragraph, containing "STRUCTURE_1rkb", creates the "Structure Box" on the page.
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<StructureSection load='1rkb' size='340' side='right'caption='[[1rkb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rkb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RKB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1rkb| PDB=1rkb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rkb OCA], [https://pdbe.org/1rkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rkb RCSB], [https://www.ebi.ac.uk/pdbsum/1rkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rkb ProSAT]</span></td></tr>
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</table>
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===The structure of adrenal gland protein AD-004===
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== Function ==
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[https://www.uniprot.org/uniprot/KAD6_HUMAN KAD6_HUMAN] Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.<ref>PMID:15630091</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15630091 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rk/1rkb_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15630091}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1RKB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RKB OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rkb ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus., Ren H, Wang L, Bennett M, Liang Y, Zheng X, Lu F, Li L, Nan J, Luo M, Eriksson S, Zhang C, Su XD, Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):303-8. Epub 2005 Jan 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15630091 15630091]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bennett, M.]]
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[[Category: Bennett M]]
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[[Category: Liang, Y.]]
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[[Category: Liang Y]]
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[[Category: Ren, H.]]
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[[Category: Ren H]]
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[[Category: Su, X D.]]
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[[Category: Su XD]]
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[[Category: Five-stranded parallel beta-sheet flanked by 7 alpha-helice]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:18:52 2008''
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Current revision

The structure of adrenal gland protein AD-004

PDB ID 1rkb

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