1p0h

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{{Seed}}
 
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[[Image:1p0h.png|left|200px]]
 
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==Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex==
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The line below this paragraph, containing "STRUCTURE_1p0h", creates the "Structure Box" on the page.
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<StructureSection load='1p0h' size='340' side='right'caption='[[1p0h]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p0h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
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{{STRUCTURE_1p0h| PDB=1p0h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0h OCA], [https://pdbe.org/1p0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0h RCSB], [https://www.ebi.ac.uk/pdbsum/1p0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0h ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex===
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== Function ==
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[https://www.uniprot.org/uniprot/MSHD_MYCTU MSHD_MYCTU] Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.<ref>PMID:12375100</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12930994}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12930994 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/1p0h_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12930994}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1P0H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0H OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p0h ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases., Vetting MW, Roderick SL, Yu M, Blanchard JS, Protein Sci. 2003 Sep;12(9):1954-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12930994 12930994]
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<references/>
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[[Category: Mycobacterium tuberculosis h37rv]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Blanchard, J S.]]
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[[Category: Large Structures]]
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[[Category: Roderick, S L.]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Vetting, M W.]]
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[[Category: Blanchard JS]]
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[[Category: Yu, M.]]
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[[Category: Roderick SL]]
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[[Category: Acetyltransferase]]
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[[Category: Vetting MW]]
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[[Category: Coenzyme a complex]]
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[[Category: Yu M]]
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[[Category: Gnat fold]]
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[[Category: Mshd]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:36:00 2008''
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Current revision

Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex

PDB ID 1p0h

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