2ai9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:13, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2ai9.png|left|200px]]
 
-
<!--
+
==S.aureus Polypeptide Deformylase==
-
The line below this paragraph, containing "STRUCTURE_2ai9", creates the "Structure Box" on the page.
+
<StructureSection load='2ai9' size='340' side='right'caption='[[2ai9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2ai9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AI9 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_2ai9| PDB=2ai9 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ai9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ai9 OCA], [https://pdbe.org/2ai9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ai9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ai9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ai9 ProSAT]</span></td></tr>
-
 
+
</table>
-
===S.aureus Polypeptide Deformylase===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/DEF_STAAU DEF_STAAU] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_12538898}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 12538898 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ai/2ai9_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_12538898}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
2AI9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AI9 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ai9 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species., Smith KJ, Petit CM, Aubart K, Smyth M, McManus E, Jones J, Fosberry A, Lewis C, Lonetto M, Christensen SB, Protein Sci. 2003 Feb;12(2):349-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12538898 12538898]
+
</StructureSection>
-
[[Category: Peptide deformylase]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
-
[[Category: Aubart, K.]]
+
[[Category: Aubart K]]
-
[[Category: Christensen, S B.]]
+
[[Category: Christensen SB]]
-
[[Category: Fosberry, A.]]
+
[[Category: Fosberry A]]
-
[[Category: Jones, J.]]
+
[[Category: Jones J]]
-
[[Category: Lewis, C.]]
+
[[Category: Lewis C]]
-
[[Category: Lonetto, M.]]
+
[[Category: Lonetto M]]
-
[[Category: McManus, E.]]
+
[[Category: McManus E]]
-
[[Category: Petit, C M.]]
+
[[Category: Petit CM]]
-
[[Category: Smith, K J.]]
+
[[Category: Smith KJ]]
-
[[Category: Smyth, M.]]
+
[[Category: Smyth M]]
-
[[Category: Hudrolase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:39:27 2008''
+

Current revision

S.aureus Polypeptide Deformylase

PDB ID 2ai9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ai9"
Personal tools