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1qzg

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{{Seed}}
 
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[[Image:1qzg.png|left|200px]]
 
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==Crystal structure of Pot1 (protection of telomere)- ssDNA complex==
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The line below this paragraph, containing "STRUCTURE_1qzg", creates the "Structure Box" on the page.
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<StructureSection load='1qzg' size='340' side='right'caption='[[1qzg]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qzg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QZG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr>
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{{STRUCTURE_1qzg| PDB=1qzg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzg OCA], [https://pdbe.org/1qzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qzg RCSB], [https://www.ebi.ac.uk/pdbsum/1qzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzg ProSAT]</span></td></tr>
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</table>
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===Crystal structure of Pot1 (protection of telomere)- ssDNA complex===
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== Function ==
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[https://www.uniprot.org/uniprot/POT1_SCHPO POT1_SCHPO] Single-stranded telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang. It binds the consensus sequence 5'-GGTTAC-3'. Regulates telomerase and telomere length.<ref>PMID:11349150</ref> <ref>PMID:12463756</ref> <ref>PMID:18535244</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_14614509}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 14614509 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/1qzg_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_14614509}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1QZG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZG OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qzg ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA., Lei M, Podell ER, Baumann P, Cech TR, Nature. 2003 Nov 13;426(6963):198-203. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14614509 14614509]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Single protein]]
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[[Category: Baumann P]]
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[[Category: Baumann, P.]]
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[[Category: Cech TR]]
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[[Category: Cech, T R.]]
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[[Category: Lei M]]
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[[Category: Lei, M.]]
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[[Category: Podell ER]]
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[[Category: Podell, E R.]]
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[[Category: Protrein-dna complex]]
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[[Category: Single-stranded telomeric dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:53:57 2008''
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Current revision

Crystal structure of Pot1 (protection of telomere)- ssDNA complex

PDB ID 1qzg

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