2i3a

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{{Seed}}
 
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[[Image:2i3a.png|left|200px]]
 
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<!--
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==Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_2i3a", creates the "Structure Box" on the page.
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<StructureSection load='2i3a' size='340' side='right'caption='[[2i3a]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2i3a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I3A FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr>
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{{STRUCTURE_2i3a| PDB=2i3a | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i3a OCA], [https://pdbe.org/2i3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i3a RCSB], [https://www.ebi.ac.uk/pdbsum/2i3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i3a ProSAT]</span></td></tr>
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</table>
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===Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis===
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== Function ==
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[https://www.uniprot.org/uniprot/ARGC_MYCTU ARGC_MYCTU]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17316682}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17316682 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/2i3a_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17316682}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2I3A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I3A OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i3a ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase from Mycobacterium tuberculosis in complex with NADP(+)., Cherney LT, Cherney MM, Garen CR, Niu C, Moradian F, James MN, J Mol Biol. 2007 Apr 13;367(5):1357-69. Epub 2007 Jan 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17316682 17316682]
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</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Large Structures]]
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[[Category: N-acetyl-gamma-glutamyl-phosphate reductase]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Single protein]]
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[[Category: Cherney LT]]
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[[Category: Cherney, L T.]]
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[[Category: Cherney MM]]
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[[Category: Cherney, M M.]]
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[[Category: Garen CR]]
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[[Category: Garen, C R.]]
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[[Category: James MNG]]
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[[Category: James, M N.G.]]
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[[Category: Moraidin F]]
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[[Category: Moraidin, F.]]
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[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
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[[Category: Dimer interface beta sandwich]]
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[[Category: Mycobacterium tuberculosis structural proteomics project]]
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[[Category: Rossmann fold]]
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[[Category: Structural genomic]]
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[[Category: Tetramer]]
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[[Category: Xmtb]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:16:37 2008''
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Current revision

Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis

PDB ID 2i3a

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