2jup

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{{Seed}}
 
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[[Image:2jup.png|left|200px]]
 
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==FBP28WW2 domain in complex with the PPLIPPPP peptide==
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The line below this paragraph, containing "STRUCTURE_2jup", creates the "Structure Box" on the page.
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<StructureSection load='2jup' size='340' side='right'caption='[[2jup]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JUP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jup OCA], [https://pdbe.org/2jup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jup RCSB], [https://www.ebi.ac.uk/pdbsum/2jup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jup ProSAT]</span></td></tr>
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{{STRUCTURE_2jup| PDB=2jup | SCENE= }}
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</table>
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== Function ==
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===FBP28WW2 domain in complex with the PPLIPPPP peptide===
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[https://www.uniprot.org/uniprot/TCRG1_MOUSE TCRG1_MOUSE] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_17915251}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 17915251 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/2jup_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_17915251}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jup ConSurf].
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2JUP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUP OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains., Ramirez-Espain X, Ruiz L, Martin-Malpartida P, Oschkinat H, Macias MJ, J Mol Biol. 2007 Nov 9;373(5):1255-68. Epub 2007 Aug 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17915251 17915251]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Synthetic construct]]
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[[Category: Macias, M J.]]
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[[Category: Macias MJ]]
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[[Category: Martin-Malpartida, P.]]
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[[Category: Martin-Malpartida P]]
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[[Category: Oschkinat, H.]]
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[[Category: Oschkinat H]]
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[[Category: Ramirez-Espain, X.]]
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[[Category: Ramirez-Espain X]]
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[[Category: Ruiz, L.]]
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[[Category: Ruiz L]]
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[[Category: Actin-binding]]
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[[Category: Alternative splicing]]
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[[Category: Cell junction]]
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[[Category: Coiled coil]]
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[[Category: Cytoplasm]]
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[[Category: Fbp28ww domain]]
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[[Category: Membrane]]
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[[Category: Nmr]]
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[[Category: Nucleus]]
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[[Category: Phosphorylation]]
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[[Category: Polymorphism]]
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[[Category: Pplipppp peptide]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:16:56 2008''
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Current revision

FBP28WW2 domain in complex with the PPLIPPPP peptide

PDB ID 2jup

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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