2dua

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{{Seed}}
 
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[[Image:2dua.png|left|200px]]
 
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==Crystal Structure of Phosphonopyruvate Hydrolase Complex with Oxalate and Mg++==
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The line below this paragraph, containing "STRUCTURE_2dua", creates the "Structure Box" on the page.
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<StructureSection load='2dua' size='340' side='right'caption='[[2dua]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2dua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Variovorax_sp._Pal2 Variovorax sp. Pal2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DUA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
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{{STRUCTURE_2dua| PDB=2dua | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dua OCA], [https://pdbe.org/2dua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dua RCSB], [https://www.ebi.ac.uk/pdbsum/2dua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dua ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Phosphonopyruvate Hydrolase Complex with Oxalate and Mg++===
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== Function ==
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[https://www.uniprot.org/uniprot/PPHA_VARSP PPHA_VARSP] Hydrolyzes phosphonopyruvate. Not active towards phosphoenolpyruvate, glycerophosphate, phospho-L-serine or phosphoglycolic acid.<ref>PMID:12697754</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16981709 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/2dua_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16981709}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2DUA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Variovorax_sp._pal2 Variovorax sp. pal2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUA OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dua ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily., Chen CC, Han Y, Niu W, Kulakova AN, Howard A, Quinn JP, Dunaway-Mariano D, Herzberg O, Biochemistry. 2006 Sep 26;45(38):11491-504. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16981709 16981709]
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<references/>
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[[Category: Single protein]]
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__TOC__
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[[Category: Variovorax sp. pal2]]
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</StructureSection>
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[[Category: Chen, C.]]
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[[Category: Large Structures]]
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[[Category: Herzberg, O.]]
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[[Category: Variovorax sp. Pal2]]
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[[Category: Pep mutase/isocitrate lyase superfamily]]
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[[Category: Chen C]]
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[[Category: Phosphonopyruvate]]
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[[Category: Herzberg O]]
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[[Category: Phosphonopyruvate hydrolase]]
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[[Category: Phosphorus-carbon bond cleavage]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:22:04 2008''
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Current revision

Crystal Structure of Phosphonopyruvate Hydrolase Complex with Oxalate and Mg++

PDB ID 2dua

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