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2d5l

From Proteopedia

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{{Seed}}
 
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[[Image:2d5l.png|left|200px]]
 
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==Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis==
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The line below this paragraph, containing "STRUCTURE_2d5l", creates the "Structure Box" on the page.
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<StructureSection load='2d5l' size='340' side='right'caption='[[2d5l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2d5l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_W83 Porphyromonas gingivalis W83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D5L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2d5l| PDB=2d5l | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5l OCA], [https://pdbe.org/2d5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d5l RCSB], [https://www.ebi.ac.uk/pdbsum/2d5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d5l ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTP_PORGI PTP_PORGI] Serine proteinase. Releases tripeptides from the free amino terminus of proteins. Has a requirement for Pro in the P1 position, but is inactivated by Pro in the P1' position.<ref>PMID:10092598</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/2d5l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d5l ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis===
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==See Also==
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*[[Tripeptidyl peptidase|Tripeptidyl peptidase]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_16914159}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16914159 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_16914159}}
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[[Category: Porphyromonas gingivalis W83]]
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[[Category: Ito K]]
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==About this Structure==
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[[Category: Nakajima Y]]
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2D5L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5L OCA].
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[[Category: Onohara Y]]
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[[Category: Xu Y]]
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==Reference==
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[[Category: Yamada N]]
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Crystal structure and mechanism of tripeptidyl activity of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis., Ito K, Nakajima Y, Xu Y, Yamada N, Onohara Y, Ito T, Matsubara F, Kabashima T, Nakayama K, Yoshimoto T, J Mol Biol. 2006 Sep 15;362(2):228-40. Epub 2006 Aug 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16914159 16914159]
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[[Category: Yoshimoto T]]
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[[Category: Porphyromonas gingivalis]]
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[[Category: Single protein]]
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[[Category: Ito, K.]]
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[[Category: Nakajima, Y.]]
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[[Category: Onohara, Y.]]
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[[Category: Xu, Y.]]
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[[Category: Yamada, N.]]
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[[Category: Yoshimoto, T.]]
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[[Category: Peptidase family s9]]
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[[Category: Prolyl oligopeptidase family]]
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[[Category: Serine peptidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:06:57 2008''
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Current revision

Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis

PDB ID 2d5l

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