2d5l
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:2d5l.png|left|200px]] | ||
- | < | + | ==Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis== |
- | + | <StructureSection load='2d5l' size='340' side='right'caption='[[2d5l]], [[Resolution|resolution]] 2.10Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2d5l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_W83 Porphyromonas gingivalis W83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D5L FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5l OCA], [https://pdbe.org/2d5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d5l RCSB], [https://www.ebi.ac.uk/pdbsum/2d5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d5l ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PTP_PORGI PTP_PORGI] Serine proteinase. Releases tripeptides from the free amino terminus of proteins. Has a requirement for Pro in the P1 position, but is inactivated by Pro in the P1' position.<ref>PMID:10092598</ref> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d5/2d5l_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d5l ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Tripeptidyl peptidase|Tripeptidyl peptidase]] | |
- | + | == References == | |
- | + | <references/> | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
- | + | [[Category: Porphyromonas gingivalis W83]] | |
- | + | [[Category: Ito K]] | |
- | + | [[Category: Nakajima Y]] | |
- | + | [[Category: Onohara Y]] | |
- | + | [[Category: Xu Y]] | |
- | == | + | [[Category: Yamada N]] |
- | + | [[Category: Yoshimoto T]] | |
- | [[Category: | + | |
- | [[Category: | + | |
- | [[Category: Ito | + | |
- | [[Category: Nakajima | + | |
- | [[Category: Onohara | + | |
- | [[Category: Xu | + | |
- | [[Category: Yamada | + | |
- | [[Category: Yoshimoto | + | |
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Current revision
Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
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