1n0e

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(New page: 200px<br /><applet load="1n0e" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n0e, resolution 2.70&Aring;" /> '''CRYSTAL STRUCTURE OF...)
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[[Image:1n0e.gif|left|200px]]<br /><applet load="1n0e" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1n0e, resolution 2.70&Aring;" />
 
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'''CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF'''<br />
 
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==Overview==
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==CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF==
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UPF0040 is a family of proteins implicated in a cellular function of, bacteria cell division. There is no structure information available on, protein of this family. We have determined the crystal structure of a, protein from Mycoplasma pneumoniae that belongs to this family using X-ray, crystallography. Structural homology search reveals that this protein has, a novel fold with no significant similarity to any proteins of known, three-dimensional structure. The crystal structures of the protein in, three different crystal forms reveal that the protein exists as a ring of, octamer. The conserved protein residues, including a highly conserved, DXXXR motif, are examined on the basis of crystal structure.
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<StructureSection load='1n0e' size='340' side='right'caption='[[1n0e]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1n0e]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N0E FirstGlance]. <br>
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1N0E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N0E OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0e OCA], [https://pdbe.org/1n0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n0e RCSB], [https://www.ebi.ac.uk/pdbsum/1n0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n0e ProSAT], [https://www.topsan.org/Proteins/BSGC/1n0e TOPSAN]</span></td></tr>
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==Reference==
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</table>
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Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif., Chen S, Jancrick J, Yokota H, Kim R, Kim SH, Proteins. 2004 Jun 1;55(4):785-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15146477 15146477]
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== Function ==
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[https://www.uniprot.org/uniprot/MRAZ_MYCPN MRAZ_MYCPN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n0e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n0e ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Mycoplasma pneumoniae]]
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[[Category: Single protein]]
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[[Category: Chen S]]
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[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
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[[Category: Jancrick J]]
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[[Category: Chen, S.]]
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[[Category: Kim R]]
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[[Category: Jancrick, J.]]
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[[Category: Kim S-H]]
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[[Category: Kim, R.]]
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[[Category: Yokota H]]
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[[Category: Kim, S.H.]]
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[[Category: Yokota, H.]]
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[[Category: berkeley structural genomics center]]
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[[Category: bsgc structure funded by nih]]
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[[Category: cell division and cell wall biosynthesis protein]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 21:51:01 2007''
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Current revision

CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF

PDB ID 1n0e

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