1sff

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{{Seed}}
 
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[[Image:1sff.png|left|200px]]
 
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==Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate==
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The line below this paragraph, containing "STRUCTURE_1sff", creates the "Structure Box" on the page.
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<StructureSection load='1sff' size='340' side='right'caption='[[1sff]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sff]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IK2:4-DEOXY-4-ACETYLYAMINO-PYRIDOXAL-5-PHOSPHATE'>IK2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1sff| PDB=1sff | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sff OCA], [https://pdbe.org/1sff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sff RCSB], [https://www.ebi.ac.uk/pdbsum/1sff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sff ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GABT_ECOLI GABT_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).<ref>PMID:20639325</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sff_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sff ConSurf].
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<div style="clear:both"></div>
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===Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate===
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==See Also==
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 15323550 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_15323550}}
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==About this Structure==
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1SFF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFF OCA].
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==Reference==
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Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase., Liu W, Peterson PE, Carter RJ, Zhou X, Langston JA, Fisher AJ, Toney MD, Biochemistry. 2004 Aug 31;43(34):10896-905. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15323550 15323550]
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[[Category: 4-aminobutyrate transaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Carter, R J.]]
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[[Category: Carter RJ]]
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[[Category: Fisher, A J.]]
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[[Category: Fisher AJ]]
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[[Category: Langston, J A.]]
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[[Category: Langston JA]]
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[[Category: Liu, W.]]
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[[Category: Liu W]]
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[[Category: Peterson, P E.]]
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[[Category: Peterson PE]]
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[[Category: Toney, M D.]]
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[[Category: Toney MD]]
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[[Category: Zhou, X.]]
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[[Category: Zhou X]]
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[[Category: Aminotransferase]]
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[[Category: Enzyme complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:51:57 2008''
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Current revision

Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate

PDB ID 1sff

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