2rfm

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{{Seed}}
 
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[[Image:2rfm.png|left|200px]]
 
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==Structure of a Thermophilic Ankyrin Repeat Protein==
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The line below this paragraph, containing "STRUCTURE_2rfm", creates the "Structure Box" on the page.
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<StructureSection load='2rfm' size='340' side='right'caption='[[2rfm]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2rfm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_volcanium Thermoplasma volcanium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RFM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene>, <scene name='pdbligand=BU2:1,3-BUTANEDIOL'>BU2</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2rfm| PDB=2rfm | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfm OCA], [https://pdbe.org/2rfm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rfm RCSB], [https://www.ebi.ac.uk/pdbsum/2rfm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rfm ProSAT]</span></td></tr>
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</table>
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===Structure of a Thermophilic Ankyrin Repeat Protein===
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== Function ==
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[https://www.uniprot.org/uniprot/Y1425_THEVO Y1425_THEVO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18305166}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18305166 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/2rfm_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18305166}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2RFM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermoplasma_volcanium Thermoplasma volcanium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFM OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rfm ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat protein., Low C, Weininger U, Neumann P, Klepsch M, Lilie H, Stubbs MT, Balbach J, Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3779-84. Epub 2008 Feb 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18305166 18305166]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Thermoplasma volcanium]]
[[Category: Thermoplasma volcanium]]
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[[Category: Balbach, J.]]
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[[Category: Balbach J]]
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[[Category: Loew, C.]]
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[[Category: Loew C]]
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[[Category: Neumann, P.]]
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[[Category: Neumann P]]
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[[Category: Stubbs, M T.]]
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[[Category: Stubbs MT]]
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[[Category: Weininger, U.]]
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[[Category: Weininger U]]
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[[Category: Ank repeat]]
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[[Category: Ankyrin repeat]]
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[[Category: Protein binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:57:52 2008''
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Current revision

Structure of a Thermophilic Ankyrin Repeat Protein

PDB ID 2rfm

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