1n38

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{{Seed}}
 
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[[Image:1n38.png|left|200px]]
 
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==reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed==
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The line below this paragraph, containing "STRUCTURE_1n38", creates the "Structure Box" on the page.
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<StructureSection load='1n38' size='340' side='right'caption='[[1n38]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n38]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mammalian_orthoreovirus_3_Dearing Mammalian orthoreovirus 3 Dearing]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N38 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CH1:3-DEOXY-CYTIDINE-5-TRIPHOSPHATE'>CH1</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=U3H:3-DEOXY-URIDINE+5-TRIPHOSPHATE'>U3H</scene></td></tr>
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{{STRUCTURE_1n38| PDB=1n38 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n38 OCA], [https://pdbe.org/1n38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n38 RCSB], [https://www.ebi.ac.uk/pdbsum/1n38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n38 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RDRP_REOVD RDRP_REOVD] RNA-directed RNA polymerase that is involved in transcription and genome replication. Following infection, it catalyzes the synthesis of fully conservative plus strands. After core assembly, which consists in recruitment of one capped plus-strand for each genomic segments and polymerase complexes, the polymerase switches mode and catalyzes the synthesis of complementary minus-strands.
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===reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed===
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12464184}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12464184 is the PubMed ID number.
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[[Category: Mammalian orthoreovirus 3 Dearing]]
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[[Category: Farsetta DL]]
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{{ABSTRACT_PUBMED_12464184}}
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[[Category: Harrison SC]]
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[[Category: Nibert ML]]
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==About this Structure==
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[[Category: Tao Y]]
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1N38 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mammalian_orthoreovirus_3 Mammalian orthoreovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N38 OCA].
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==Reference==
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RNA synthesis in a cage--structural studies of reovirus polymerase lambda3., Tao Y, Farsetta DL, Nibert ML, Harrison SC, Cell. 2002 Nov 27;111(5):733-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12464184 12464184]
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[[Category: Mammalian orthoreovirus 3]]
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[[Category: Single protein]]
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[[Category: Farsetta, D L.]]
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[[Category: Harrison, S C.]]
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[[Category: Nibert, M L.]]
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[[Category: Tao, Y.]]
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[[Category: Bracelet]]
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[[Category: Right hand configuration]]
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[[Category: Rna polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:06:18 2008''
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Current revision

reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed

PDB ID 1n38

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OCA

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