1nlq

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{{Seed}}
 
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[[Image:1nlq.png|left|200px]]
 
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==The crystal structure of Drosophila NLP-core provides insight into pentamer formation and histone binding==
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The line below this paragraph, containing "STRUCTURE_1nlq", creates the "Structure Box" on the page.
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<StructureSection load='1nlq' size='340' side='right'caption='[[1nlq]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nlq]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NLQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1nlq| PDB=1nlq | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nlq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nlq OCA], [https://pdbe.org/1nlq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nlq RCSB], [https://www.ebi.ac.uk/pdbsum/1nlq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nlq ProSAT]</span></td></tr>
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</table>
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===The crystal structure of Drosophila NLP-core provides insight into pentamer formation and histone binding===
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== Function ==
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[https://www.uniprot.org/uniprot/NLP_DROME NLP_DROME] Binds to core histones and functions in the ATP-facilitated assembly of approximately regularly spaced nucleosomal arrays. May participate in parallel with other histone-binding proteins such as NAP-1.<ref>PMID:8798787</ref> <ref>PMID:9087911</ref> Isoform 2 is inactive for chromatin assembly. In vitro it appears to form a high molecular mass aggregate with the core histones.<ref>PMID:8798787</ref> <ref>PMID:9087911</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12575937}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12575937 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nl/1nlq_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12575937}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1NLQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NLQ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nlq ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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The crystal structure of Drosophila NLP-core provides insight into pentamer formation and histone binding., Namboodiri VM, Dutta S, Akey IV, Head JF, Akey CW, Structure. 2003 Feb;11(2):175-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12575937 12575937]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Akey, C W.]]
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[[Category: Akey CW]]
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[[Category: Akey, I V.]]
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[[Category: Akey IV]]
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[[Category: Dutta, S.]]
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[[Category: Dutta S]]
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[[Category: Head, J F.]]
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[[Category: Head JF]]
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[[Category: Namboodiri, V M.H.]]
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[[Category: Namboodiri VMH]]
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[[Category: Chaperone]]
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[[Category: Dnlp]]
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[[Category: Histone binding]]
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[[Category: Nucleoplasmin]]
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[[Category: X-ray crystallography]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:12:33 2008''
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Current revision

The crystal structure of Drosophila NLP-core provides insight into pentamer formation and histone binding

PDB ID 1nlq

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