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1r5w

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{{Seed}}
 
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[[Image:1r5w.png|left|200px]]
 
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==Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation==
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The line below this paragraph, containing "STRUCTURE_1r5w", creates the "Structure Box" on the page.
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<StructureSection load='1r5w' size='340' side='right'caption='[[1r5w]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r5w]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R5W FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r5w OCA], [https://pdbe.org/1r5w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r5w RCSB], [https://www.ebi.ac.uk/pdbsum/1r5w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r5w ProSAT]</span></td></tr>
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{{STRUCTURE_1r5w| PDB=1r5w | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HA22_MOUSE HA22_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/1r5w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r5w ConSurf].
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<div style="clear:both"></div>
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===Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation===
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==See Also==
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC II 3D structures|MHC II 3D structures]]
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<!--
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_14690592}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 14690592 is the PubMed ID number.
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[[Category: Large Structures]]
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-->
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{{ABSTRACT_PUBMED_14690592}}
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==About this Structure==
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1R5W is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5W OCA].
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==Reference==
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Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation., Krogsgaard M, Prado N, Adams EJ, He XL, Chow DC, Wilson DB, Garcia KC, Davis MM, Mol Cell. 2003 Dec;12(6):1367-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14690592 14690592]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Adams E]]
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[[Category: Adams, E.]]
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[[Category: Chow DC]]
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[[Category: Chow, D C.]]
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[[Category: Davis MM]]
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[[Category: Davis, M M.]]
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[[Category: Garcia KC]]
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[[Category: Garcia, K C.]]
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[[Category: He X]]
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[[Category: He, X.]]
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[[Category: Krogsgaard M]]
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[[Category: Krogsgaard, M.]]
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[[Category: Prado N]]
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[[Category: Prado, N.]]
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[[Category: Wilson DB]]
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[[Category: Wilson, D B.]]
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[[Category: Crystal structure]]
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[[Category: Mhc class ii]]
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[[Category: Structural rearangement]]
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[[Category: Tcr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:46:46 2008''
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Current revision

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation

PDB ID 1r5w

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