1otv

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{{Seed}}
 
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[[Image:1otv.png|left|200px]]
 
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<!--
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==PqqC, Pyrroloquinolinquinone Synthase C==
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The line below this paragraph, containing "STRUCTURE_1otv", creates the "Structure Box" on the page.
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<StructureSection load='1otv' size='340' side='right'caption='[[1otv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1otv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otv OCA], [https://pdbe.org/1otv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otv RCSB], [https://www.ebi.ac.uk/pdbsum/1otv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otv ProSAT]</span></td></tr>
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{{STRUCTURE_1otv| PDB=1otv | SCENE= }}
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</table>
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== Function ==
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===PqqC, Pyrroloquinolinquinone Synthase C===
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[https://www.uniprot.org/uniprot/PQQC_KLEPN PQQC_KLEPN] Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.<ref>PMID:7665488</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15148379}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15148379 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15148379}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1otv ConSurf].
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1OTV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTV OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone., Magnusson OT, Toyama H, Saeki M, Rojas A, Reed JC, Liddington RC, Klinman JP, Schwarzenbacher R, Proc Natl Acad Sci U S A. 2004 May 25;101(21):7913-8. Epub 2004 May 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15148379 15148379]
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__TOC__
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</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Adachi, O.]]
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[[Category: Adachi O]]
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[[Category: Klinman, J P.]]
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[[Category: Klinman JP]]
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[[Category: Magnusson, O T.]]
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[[Category: Magnusson OT]]
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[[Category: Reed, J C.]]
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[[Category: Reed JC]]
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[[Category: Rojas, A.]]
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[[Category: Rojas A]]
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[[Category: SChwarzenbacher, R.]]
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[[Category: SChwarzenbacher R]]
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[[Category: Saeki, M.]]
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[[Category: Saeki M]]
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[[Category: Toyama, H.]]
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[[Category: Toyama H]]
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[[Category: Dimer]]
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[[Category: Pqq biosynthesis enzyme]]
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[[Category: Seven helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:54:34 2008''
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Current revision

PqqC, Pyrroloquinolinquinone Synthase C

PDB ID 1otv

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