2qst

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{{Seed}}
 
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[[Image:2qst.png|left|200px]]
 
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==Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)==
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The line below this paragraph, containing "STRUCTURE_2qst", creates the "Structure Box" on the page.
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<StructureSection load='2qst' size='340' side='right'caption='[[2qst]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qst]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QST FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qst OCA], [https://pdbe.org/2qst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qst RCSB], [https://www.ebi.ac.uk/pdbsum/2qst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qst ProSAT]</span></td></tr>
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{{STRUCTURE_2qst| PDB=2qst | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)===
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[https://www.uniprot.org/uniprot/CEAM5_HUMAN CEAM5_HUMAN] Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.<ref>PMID:10864933</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18086185 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qst_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18086185}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qst ConSurf].
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2QST is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QST OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation., Korotkova N, Yang Y, Le Trong I, Cota E, Demeler B, Marchant J, Thomas WE, Stenkamp RE, Moseley SL, Matthews S, Mol Microbiol. 2008 Jan;67(2):420-34. Epub 2007 Dec 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18086185 18086185]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Korotkova, N.]]
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[[Category: Korotkova N]]
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[[Category: Moseley, S L.]]
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[[Category: Le Trong I]]
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[[Category: Stenkamp, R E.]]
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[[Category: Moseley SL]]
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[[Category: Trong, I Le.]]
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[[Category: Stenkamp RE]]
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[[Category: Cell adhesion]]
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[[Category: Glycoprotein]]
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[[Category: Gpi-anchor]]
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[[Category: Immunoglobulin domain]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Polymorphism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:23:09 2008''
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Current revision

Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA)

PDB ID 2qst

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