1tzp

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{{Seed}}
 
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[[Image:1tzp.png|left|200px]]
 
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==MEPA, inactive form without ZN in P21==
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The line below this paragraph, containing "STRUCTURE_1tzp", creates the "Structure Box" on the page.
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<StructureSection load='1tzp' size='340' side='right'caption='[[1tzp]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tzp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1tzp| PDB=1tzp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tzp OCA], [https://pdbe.org/1tzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tzp RCSB], [https://www.ebi.ac.uk/pdbsum/1tzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tzp ProSAT]</span></td></tr>
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</table>
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===MEPA, inactive form without ZN in P21===
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== Function ==
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[https://www.uniprot.org/uniprot/MEPA_ECOLI MEPA_ECOLI] Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein.<ref>PMID:15292190</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15292190}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15292190 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tzp_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15292190}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1TZP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZP OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tzp ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Peptidoglycan amidase MepA is a LAS metallopeptidase., Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M, J Biol Chem. 2004 Oct 15;279(42):43982-9. Epub 2004 Jul 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15292190 15292190]
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<references/>
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__TOC__
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Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases., Bochtler M, Odintsov SG, Marcyjaniak M, Sabala I, Protein Sci. 2004 Apr;13(4):854-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15044722 15044722]
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</StructureSection>
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Latent LytM at 1.3A resolution., Odintsov SG, Sabala I, Marcyjaniak M, Bochtler M, J Mol Biol. 2004 Jan 16;335(3):775-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14687573 14687573]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bochtler, M.]]
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[[Category: Bochtler M]]
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[[Category: Marcyjaniak, M.]]
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[[Category: Marcyjaniak M]]
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[[Category: Odintsov, S G.]]
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[[Category: Odintsov SG]]
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[[Category: Sabala, I.]]
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[[Category: Sabala I]]
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[[Category: Las enzyme]]
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[[Category: Metallopeptidase]]
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[[Category: Peptidoglycan hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:27:56 2008''
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Current revision

MEPA, inactive form without ZN in P21

PDB ID 1tzp

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