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Template:STRUCTURE 1r0p

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Current revision

1r0p, resolution 1.80Å ()

Ligands:

Gene:

MET (Homo sapiens)

Activity:

Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2

Structural annotation:
Resources:	CATH : 1R0Pa01, 1R0Pa02 InterPro : Ipr001245, Ipr002165, Ipr001627, Ipr000719, Ipr014756, Ipr008266, Ipr011009, Ipr002909, Ipr003659 Pfam : PF07714 SCOP : d1r0pa_ UniProt : P08581

Functional annotation:
Cellular component:	membrane fraction integral to plasma membrane membrane integral to membrane basal plasma membrane
Biological process:	myoblast proliferation muscle development hepatocyte growth factor receptor signaling pathway cell proliferation protein amino acid phosphorylation signal transduction activation of MAPK activity adult behavior brain development multicellular organismal development protein amino acid autophosphorylation cell surface receptor linked signal transduction
Molecular function:	hepatocyte growth factor receptor activity receptor activity nucleotide binding protein-tyrosine kinase activity kinase activity protein kinase activity protein binding transferase activity ATP binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1r0p"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1r0p, resolution 1.80&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1r0p]], [[Resolution|resolution]] 1.80&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |LIGAND= <scene name='pdbligand=KSA:K-252A'>KSA</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span>
 |GENE= MET ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05058 PTKc_Met_Ron], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00220 S_TKc]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1r0p RCSB], [http://www.ebi.ac.uk/pdbsum/1r0p PDBsum]</span>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r0p OCA], [http://www.ebi.ac.uk/pdbsum/1r0p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1r0p RCSB]</span>
 |FUNCTION={{GO|id=GO:0005008 | text = hepatocyte growth factor receptor activity}}{{GO|id=GO:0004872 | text = receptor activity}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0004713 | text = protein-tyrosine kinase activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0005524 | text = ATP binding}}
 |PROCESS={{GO|id=GO:0051450 | text = myoblast proliferation}}{{GO|id=GO:0007517 | text = muscle development}}{{GO|id=GO:0048012 | text = hepatocyte growth factor receptor signaling pathway}}{{GO|id=GO:0008283 | text = cell proliferation}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0000187 | text = activation of MAPK activity}}{{GO|id=GO:0030534 | text = adult behavior}}{{GO|id=GO:0007420 | text = brain development}}{{GO|id=GO:0007275 | text = multicellular organismal development}}{{GO|id=GO:0046777 | text = protein amino acid autophosphorylation}}{{GO|id=GO:0007166 | text = cell surface receptor linked signal transduction}}
 |COMPONENT={{GO|id=GO:0005624 | text = membrane fraction}}{{GO|id=GO:0005887 | text = integral to plasma membrane}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0016021 | text = integral to membrane}}{{GO|id=GO:0009925 | text = basal plasma membrane}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1r0pA01 1R0Pa01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1r0pA02 1R0Pa02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001245 Ipr001245], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002165 Ipr002165], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001627 Ipr001627], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000719 Ipr000719], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014756 Ipr014756], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008266 Ipr008266], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011009 Ipr011009], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002909 Ipr002909], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003659 Ipr003659]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF07714 PF07714]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=96734 d1r0pa_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P08581 P08581]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=MET MET]</span>
+|uPDB=1R0P|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1r0p_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1r0p

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