1u5p

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{{Seed}}
 
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[[Image:1u5p.png|left|200px]]
 
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==Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin==
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The line below this paragraph, containing "STRUCTURE_1u5p", creates the "Structure Box" on the page.
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<StructureSection load='1u5p' size='340' side='right'caption='[[1u5p]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1u5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1u5p| PDB=1u5p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5p OCA], [https://pdbe.org/1u5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5p RCSB], [https://www.ebi.ac.uk/pdbsum/1u5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u5/1u5p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5p ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin===
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==See Also==
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*[[Spectrin 3D structures|Spectrin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15522301}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15522301 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15522301}}
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==About this Structure==
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1U5P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5P OCA].
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==Reference==
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Independent movement, dimerization and stability of tandem repeats of chicken brain alpha-spectrin., Kusunoki H, Minasov G, Macdonald RI, Mondragon A, J Mol Biol. 2004 Nov 19;344(2):495-511. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15522301 15522301]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kusunoki, H.]]
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[[Category: Kusunoki H]]
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[[Category: MacDonald, R I.]]
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[[Category: MacDonald RI]]
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[[Category: Minasov, G.]]
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[[Category: Minasov G]]
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[[Category: Mondragon, A.]]
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[[Category: Mondragon A]]
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[[Category: 3-helix coiled coil]]
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[[Category: Alpha spectrin]]
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[[Category: Alpha-helical linker region]]
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[[Category: Two repeats of spectrin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:59:19 2008''
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Current revision

Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin

PDB ID 1u5p

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