1w9z

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{{Seed}}
 
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[[Image:1w9z.png|left|200px]]
 
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==Structure of Bannavirus VP9==
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The line below this paragraph, containing "STRUCTURE_1w9z", creates the "Structure Box" on the page.
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<StructureSection load='1w9z' size='340' side='right'caption='[[1w9z]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1w9z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Banna_virus Banna virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W9Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9z OCA], [https://pdbe.org/1w9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w9z RCSB], [https://www.ebi.ac.uk/pdbsum/1w9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9z ProSAT]</span></td></tr>
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{{STRUCTURE_1w9z| PDB=1w9z | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9YWN5_9VIRU Q9YWN5_9VIRU]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Banna virus (BAV: genus Seadornavirus, family Reoviridae) has a double-shelled morphology similar to rotavirus and bluetongue virus. The structure of BAV outer-capsid protein VP9 was determined by X-ray crystallography at 2.6 A resolution, revealing a trimeric molecule, held together by an N-terminal helical bundle, reminiscent of coiled-coil structures found in fusion-active proteins such as HIV gp41. The major domain of VP9 contains stacked beta sheets with marked structural similarities to the receptor binding protein VP8 of rotavirus. Anti-VP9 antibodies neutralize viral infectivity, and, remarkably, pretreatment of cells with trimeric VP9 increased viral infectivity, indicating that VP9 is involved in virus attachment to cell surface and subsequent internalization. Sequence similarities were also detected between BAV VP10 and VP5 portion of rotavirus VP4, suggesting that the receptor binding and internalization apparatus, which is a single gene product activated by proteoloysis in rotavirus, is the product of two separate genome segments in BAV.
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===STRUCTURE OF BANNAVIRUS VP9===
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The structure and function of the outer coat protein VP9 of Banna virus.,Mohd Jaafar F, Attoui H, Bahar MW, Siebold C, Sutton G, Mertens PP, De Micco P, Stuart DI, Grimes JM, De Lamballerie X Structure. 2005 Jan;13(1):17-28. PMID:15642258<ref>PMID:15642258</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 1w9z" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15642258 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15642258}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1W9Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Banna_virus Banna virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9Z OCA].
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==Reference==
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The structure and function of the outer coat protein VP9 of Banna virus., Mohd Jaafar F, Attoui H, Bahar MW, Siebold C, Sutton G, Mertens PP, De Micco P, Stuart DI, Grimes JM, De Lamballerie X, Structure. 2005 Jan;13(1):17-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15642258 15642258]
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[[Category: Banna virus]]
[[Category: Banna virus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Attoui, H.]]
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[[Category: Attoui H]]
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[[Category: Bahar, M W.]]
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[[Category: Bahar MW]]
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[[Category: Grimes, J M.]]
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[[Category: Grimes JM]]
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[[Category: Jaafar, F M.]]
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[[Category: Jaafar FM]]
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[[Category: Lamballerie, X.]]
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[[Category: Lamballerie X]]
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[[Category: Mertens, P P.C.]]
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[[Category: Mertens PPC]]
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[[Category: Micco, P.]]
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[[Category: Micco P]]
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[[Category: Siebold, C.]]
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[[Category: Siebold C]]
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[[Category: Stuart, D I.]]
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[[Category: Stuart DI]]
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[[Category: Sutton, G.]]
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[[Category: Sutton G]]
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[[Category: Dsrna virus]]
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[[Category: Outer core protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:00:34 2008''
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Current revision

Structure of Bannavirus VP9

PDB ID 1w9z

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