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1of9

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{{Seed}}
 
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[[Image:1of9.png|left|200px]]
 
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==Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)==
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The line below this paragraph, containing "STRUCTURE_1of9", creates the "Structure Box" on the page.
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<StructureSection load='1of9' size='340' side='right'caption='[[1of9]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1of9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OF9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1of9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1of9 OCA], [https://pdbe.org/1of9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1of9 RCSB], [https://www.ebi.ac.uk/pdbsum/1of9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1of9 ProSAT]</span></td></tr>
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{{STRUCTURE_1of9| PDB=1of9 | SCENE= }}
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</table>
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== Function ==
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===SOLUTION STRUCTURE OF THE PORE FORMING TOXIN OF ENTAMOEBA HISTOLYTICA (AMOEBAPORE A)===
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[https://www.uniprot.org/uniprot/PFPA_ENTHI PFPA_ENTHI] Forms pores in the cytoplasmic membrane of host cells. Has antibacterial activity against M.luteus, no activity against E.coli. Implicated in the cytolytic activity of the parasite.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_14970207}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 14970207 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/1of9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_14970207}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1of9 ConSurf].
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1OF9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Entamoeba_histolytica Entamoeba histolytica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF9 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Solution structure of the pore-forming protein of Entamoeba histolytica., Hecht O, Van Nuland NA, Schleinkofer K, Dingley AJ, Bruhn H, Leippe M, Grotzinger J, J Biol Chem. 2004 Apr 23;279(17):17834-41. Epub 2004 Feb 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14970207 14970207]
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[[Category: Entamoeba histolytica]]
[[Category: Entamoeba histolytica]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bruhn, H.]]
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[[Category: Bruhn H]]
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[[Category: Dingley, A J.]]
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[[Category: Dingley AJ]]
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[[Category: Grotzinger, J.]]
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[[Category: Grotzinger J]]
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[[Category: Hecht, O.]]
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[[Category: Hecht O]]
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[[Category: Leippe, M.]]
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[[Category: Leippe M]]
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[[Category: Nuland, N Van.]]
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[[Category: Schleinkofer K]]
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[[Category: Schleinkofer, K.]]
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[[Category: Van Nuland N]]
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[[Category: Amoebapore some]]
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[[Category: Pore forming]]
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[[Category: Saplip]]
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[[Category: Toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:12:01 2008''
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Current revision

Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)

PDB ID 1of9

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