2jxu

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{{Seed}}
 
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[[Image:2jxu.png|left|200px]]
 
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==NMR solution structure of KP-TerB, a tellurite resistance protein from Klebsiella pneumoniae==
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The line below this paragraph, containing "STRUCTURE_2jxu", creates the "Structure Box" on the page.
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<StructureSection load='2jxu' size='340' side='right'caption='[[2jxu]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_NTUH-K2044 Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JXU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jxu OCA], [https://pdbe.org/2jxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jxu RCSB], [https://www.ebi.ac.uk/pdbsum/2jxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jxu ProSAT]</span></td></tr>
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{{STRUCTURE_2jxu| PDB=2jxu | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6U646_KLEPN Q6U646_KLEPN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/2jxu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jxu ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Klebsiella pneumoniae (KP), a Gram-negative bacterium, is a common cause of hospital-acquired bacterial infections worldwide. Tellurium (Te) compounds, although relatively rare in the environment, have a long history as antimicrobial and therapeutic agents. In bacteria, tellurite (TeO(3) (-2)) resistance is conferred by the ter (Te(r)) operon (terZABCDEF). Here, on the basis of 2593 restraints derived from NMR analysis, we report the NMR structure of TerB protein (151 amino acids) of KP (KP-TerB), which is mainly composed of seven alpha-helices and a 3(10) helix, with helices II to V apparently forming a four-helix bundle. The ensemble of 20 NMR structures was well-defined, with a RMSD of 0.32 +/- 0.06 A for backbone atoms and 1.11 +/- 0.07 A for heavy atoms, respectively. A unique property of the KP-TerB structure is that the positively and negatively charged clusters are formed by the N-terminal positively and C-terminal negatively charged residues, respectively. To the best of our knowledge, the protein sequence and structures of KP-TerB are unique.
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===NMR solution structure of KP-TerB, a tellurite resistance protein from Klebsiella pneumoniae===
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NMR solution structure of KP-TerB, a tellurite-resistance protein from Klebsiella pneumoniae.,Chiang SK, Lou YC, Chen C Protein Sci. 2008 Apr;17(4):785-9. Epub 2008 Feb 27. PMID:18305192<ref>PMID:18305192</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_18305192}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2jxu" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 18305192 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_18305192}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]]
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2JXU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JXU OCA].
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[[Category: Large Structures]]
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[[Category: Chen C]]
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==Reference==
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[[Category: Chiang S-K]]
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NMR solution structure of KP-TerB, a tellurite-resistance protein from Klebsiella pneumoniae., Chiang SK, Lou YC, Chen C, Protein Sci. 2008 Feb 27;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18305192 18305192]
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[[Category: Lou Y-C]]
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[[Category: Klebsiella pneumoniae]]
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[[Category: Single protein]]
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[[Category: Chen, C.]]
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[[Category: Chiang, S K.]]
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[[Category: Lou, Y C.]]
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[[Category: Klebsiella pneumoniae]]
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[[Category: Kp-terb]]
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[[Category: Plasmid]]
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[[Category: Tellurite resistance protein]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:16:21 2008''
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Current revision

NMR solution structure of KP-TerB, a tellurite resistance protein from Klebsiella pneumoniae

PDB ID 2jxu

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